DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32147 and PGPEP1L

DIOPT Version :9

Sequence 1:	NP_730035.1	Gene:	CG32147 / 251690	FlyBaseID:	FBgn0047178	Length:	224	Species:	Drosophila melanogaster
Sequence 2:	XP_011519556.1	Gene:	PGPEP1L / 145814	HGNCID:	27080	Length:	287	Species:	Homo sapiens

Alignment Length:	217	Identity:	62/217 - (28%)
Similarity:	99/217 - (45%)	Gaps:	24/217 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SDRKLIVVSGFGPFLGHEAVNASWEAVKLLPEILTHDGIEYDLEKRLVSVEYGAVDEAVAEIWK- 67
            |....:||:|||||..| .||:||||||.|.::...:.....|....:.|:|......|..||:
Human    72 SQPSCVVVTGFGPFRQH-LVNSSWEAVKELSKLGLGNETVVQLRTLELPVDYREAKRRVTGIWED 135

  Fly    68 RQPYLVIHVGVSGVAKCVYIEKLAYNHKFRRADNCDKKLANGTCELPNNGHANVLKTELDVDKIV 132
            .||.||:|||:...||.:.:|:...|..:|.||........|.| ||  |..:||::.:.:..:.
Human   136 HQPQLVVHVGMDTAAKAIILEQSGKNQGYRDADIRSFWPEGGVC-LP--GSPDVLESGVCMKAVC 197

  Fly   133 AVVNENCADCVGPTQQPTHNDNLKSLSATKASKNVGDFLCGYIYLKSLDMDRKRSLFVHVPPVDR 197
            ..|.....|.:                   .|::.|.::|.|.|..||...:..:..:||||:.|
Human   198 KRVAVEGVDVI-------------------FSRDAGRYVCDYTYYLSLHHGKGCAALIHVPPLSR 243

  Fly   198 PFSSVKTSEILFSIVEQCIQQV 219
            ...:......|..|:::.:::|
Human   244 GLPASLLGRALRVIIQEMLEEV 265

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32147	NP_730035.1	Peptidase_C15	7..222	CDD:238279	61/214 (29%)
PGPEP1L	XP_011519556.1	Peptidase_C15	76..243	CDD:238279	57/189 (30%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165141482
Domainoid	1	1.000	76	1.000	Domainoid score	I8971
eggNOG	1	0.900	-	-		E1_COG2039
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	106	1.000	Inparanoid score	I4939
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1248044at2759
OrthoFinder	1	1.000	-	-		FOG0002733
OrthoInspector	1	1.000	-	-		otm41417
orthoMCL	1	0.900	-	-		OOG6_101530
Panther	1	1.100	-	-	O	PTHR23402
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2169
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	13	12.760