DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mas1 and CCHa1-R

DIOPT Version :9

Sequence 1:	NP_036889.1	Gene:	Mas1 / 25153	RGDID:	3049	Length:	324	Species:	Rattus norvegicus
Sequence 2:	NP_611241.2	Gene:	CCHa1-R / 37004	FlyBaseID:	FBgn0050106	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	344	Identity:	78/344 - (22%)
Similarity:	140/344 - (40%)	Gaps:	87/344 - (25%)

- Green bases have known domain annotations that are detailed below.

  Rat    18 SSRNAS-LGTSHPP------------IPIVHWVIMSISPLGFVENG-ILLWFLCFRMRRNPFTVY 68
            ||.|.| |.|:..|            :||:..:|..:..||   || :::.||..|..||....|
  Fly    58 SSENFSELVTTETPYVPYGRRPETYIVPILFALIFVVGVLG---NGTLIVVFLSVRQMRNVPNTY 119

  Rat    69 ITHLSIADISLLF-CIFILSIDYALDY------ELSSGHYYTIVTLSVTFLFGYNTGLYLLTAIS 126
            |..|::||:.::. .:.:.|..|.::|      ..|...:...|::.|:        ::.|||:|
  Fly   120 ILSLALADLLVIITTVPLASTVYTVEYWPYGSFLCSLSEFMKDVSIGVS--------VFTLTALS 176

  Rat   127 VERCLSVLYPI-WYRCH----RPKHQSAFVCALLWALSCL---------------VTTMEYVMCI 171
            .:|..:::.|: .:..|    |....:......:|.|:.|               :.....|:|.
  Fly   177 GDRYFAIVDPLRKFHAHGGGRRATRMTLATAVSIWLLAILCGLPALIGSNLKHLGINEKSIVICY 241

  Rat   172 DSGEE---SHSQSDCRAVIIFIAILSFLVFTPLMLVSSTILVVKIRKNTWASHS----------- 222
            ...||   ::::|        :.:|.|||:..:.||...:..|.|..:...|.|
  Fly   242 PYPEEWGINYAKS--------MVLLHFLVYYAIPLVVIAVFYVLIALHLMYSASVPGEIQGAVRQ 298

  Rat   223 ----SKLYIVIMVTIIIFLIFAMPMRVLYLLYYEYWSTFGNLHN--------ISLLFSTINSSAN 275
                .|:.:.::..::||.|..:|..|.:|.:| :|.|..:.:|        ::...|..||.||
  Fly   299 VRARRKVAVTVLAFVVIFGICFLPYHVFFLWFY-FWPTAQDDYNAFWHVLRIVAYCMSFANSCAN 362

  Rat   276 PFIYFFVGSSKKKRFRESL 294
            |...:||..:.:|.|...|
  Fly   363 PVALYFVSGAFRKHFNRYL 381

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mas1	NP_036889.1	7tmA_MrgprH	32..306	CDD:320238	71/317 (22%)
		TM helix 1	34..58	CDD:320238	7/24 (29%)
		TM helix 2	66..88	CDD:320238	5/22 (23%)
		TM helix 3	107..127	CDD:320238	4/19 (21%)
		TM helix 4	150..166	CDD:320238	3/30 (10%)
		TM helix 5	189..212	CDD:320238	6/22 (27%)
		TM helix 6	226..248	CDD:320238	5/21 (24%)
		TM helix 7	258..283	CDD:320238	8/32 (25%)
CCHa1-R	NP_611241.2	7tm_4	88..>188	CDD:304433	27/110 (25%)
CCHa1-R	NP_611241.2	7tm_1	98..364	CDD:278431	61/285 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000