Protein Alignment Cyp19a1 and Cyp4d20

DIOPT Version :9

• Sequence 1: NP_058781.2
• Gene: Cyp19a1 / 25147
• RGDID: 2457
• Length: 503
• Species: Rattus norvegicus
• Sequence 2: NP_647723.2
• Gene: Cyp4d20 / 38311
• FlyBaseID: FBgn0035344
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 508
• Identity: 116/508 - (22%)
• Similarity: 213/508 - (41%)
• Gaps: 97/508 - (19%)

  Rat    26 MPLLLIMGLLLLIRNCE-----------SSSSIPGPGYCLGIGPLISHG-RFLWMG----IGSAC 74
            |.|.||.|.|:|:...:           ..|:||||   :.| |::..| :.|.:|    ||...
  Fly     1 MWLTLITGALILLLTWDFGRKRQRVLAFEKSAIPGP---ISI-PILGCGLQALHLGAENIIGWVG 61

  Rat    75 NYYNKMYGEFMRVWISGEETLIISKSSSMVHVMKHSNYISRFGSKRGLQCIGMHE-------NGI 132
            ..::| ||:..|.||.| |:||.:|.......:..|..:...|.        ::|       :|:
  Fly    62 EKFDK-YGKTFRFWILG-ESLIYTKDLQYFETILSSTTLLEKGQ--------LYEYLRPFLNDGL 116

  Rat   133 IFNNNPSLWRTVRPFFMKALTGPGLIRMVEVCVESIKQH----LDRLGDVTDNSGYVDVVTLMRH 193
            :.:.... |...|..|..|..    .:::|..||.:.:|    :|.|..|.|....||::..:..
  Fly   117 LVSTGRK-WHARRKIFTHAFH----FKVLEHYVEIMDRHSSVMVDNLRKVADGKTAVDMLKYVSL 176

  Rat   194 IMLDTSNTLFLGIPLDESS-----IVKKIQGYFNAWQALLIKPNIFFKIS----WLY-------- 241
            ..||......:|:.::..:     .:|.::      ..:.|:|:..|:.|    ||:
  Fly   177 AALDVITEAAMGVQVNAQNDPDFPYIKALK------SVVYIQPDRMFRFSRRYNWLFPLAAPLLH 235

  Rat   242 RKYERSVKDLKDEIEILVEKKRQKVSSAE--------KLEDC----------MDFATDLIFAERR 288
            |:....::.:.|..:.::.::|:.|..|:        .|.|.          :|..  |..:...
  Fly   236 RQLLSDIRVMHDFTDKVISERRETVRRAKADGTYRPLSLGDAEIGSKSQMALLDIL--LQSSINN 298

  Rat   289 GDLTKENVNQCILEMLIAAPDTMSVTLYVMLLLIAEYPEVETAILKEIHTVVG---DRDIRIGDV 350
            ..|:..::.:.:...:....||.|..:...|..||.:|||:..|.:|:..|:|   ...:....:
  Fly   299 QPLSDADIREEVDTFMFEGDDTTSSGVSHALYAIARHPEVQQRIFEELQRVLGPDASAPVTQAQL 363

  Rat   351 QNLKVVENFINESLRYQPVVDLVMRRALEDDVIDGYPVKKGTNIILNIGRMHR-LEYFPKPNEFT 414
            |:||.::..|.|::|..|.|..:.|.|.::..|....:...|:|.|.:...|| ..|||.|..|.
  Fly   364 QDLKYLDCVIKETMRLYPPVPAIGRHAQKELEIGDKTIPANTSIYLVLYYAHRDANYFPDPLSFR 428

  Rat   415 LENFEKNVPYRY----FQPFGFGPRSCAGKYIAMVMMKVVLVTLLKRFHVKTL 463
            .|.|.::....:    :.||..||::|.|:..|::.|||::..:|:.:.:..|
  Fly   429 PERFLEDQEQGHNTFAYVPFSAGPKNCIGQKFAVLEMKVLISKVLRFYELLPL 481

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp19a1	NP_058781.2	CYP19A1	72..485	CDD:410709	97/446 (22%)
Cyp4d20	NP_647723.2	p450	34..493	CDD:278495	107/475 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1247045at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24291
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.950