Protein Alignment FTL and Fer1HCH

DIOPT Version :9

• Sequence 1: NP_000137.2
• Gene: FTL / 2512
• HGNCID: 3999
• Length: 175
• Species: Homo sapiens
• Sequence 2: NP_001263104.1
• Gene: Fer1HCH / 46415
• FlyBaseID: FBgn0015222
• Length: 245
• Species: Drosophila melanogaster
• Alignment Length: 177
• Identity: 48/177 - (27%)
• Similarity: 91/177 - (51%)
• Gaps: 13/177 - (7%)

Human     4 QIRQNYSTDVEAAVNSLVNLY---LQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYER 65
            :|.:::....:|.:..:.|..   :.|||.||::|.||.||.|...|.:..|.:.|:|:||...:
  Fly    69 EITKDWVDMKDACIKGMRNQIQEEINASYQYLAMGAYFSRDTVNRPGFAEHFFKAAKEEREHGSK 133

Human    66 LLKMQNQRG----GRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDP-- 124
            |::..:.||    |.:...::...|:.||.....|:..|:.||.|:.:::..|  :.:....|
  Fly   134 LVEYLSMRGQLTEGVSDLINVPTVAKQEWTDGAAALSDALDLEIKVTKSIRKL--IQTCENKPYN 196

Human   125 --HLCDFLETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFER 169
              ||.|:|...:|:|::...:::...||.|.::......|||:||::
  Fly   197 HYHLVDYLTGVYLEEQLHGQRELAGKLTTLKKMMDTNGELGEFLFDK 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FTL	NP_000137.2	Ferritin	10..169	CDD:153098	47/169 (28%)
		Catalytic site for iron oxidation	54..61		2/6 (33%)
Fer1HCH	NP_001263104.1	Euk_Ferritin	79..243	CDD:153114	47/165 (28%)
		Ferritin	82..229	CDD:278632	41/148 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249457at2759
OrthoFinder	1	1.000	-	-		FOG0000169
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11431
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.920