Protein Alignment FTL and Fer3HCH

DIOPT Version :10

• Sequence 1: NP_000137.2
• Gene: FTL / 2512
• HGNCID: 3999
• Length: 175
• Species: Homo sapiens
• Sequence 2: NP_572854.1
• Gene: Fer3HCH / 32260
• FlyBaseID: FBgn0030449
• Length: 186
• Species: Drosophila melanogaster
• Alignment Length: 169
• Identity: 61/169 - (36%)
• Similarity: 106/169 - (62%)
• Gaps: 4/169 - (2%)

Human     1 MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYLSLGFYFDRDDVALEGVSHFFRELAEEKREGYER 65
            |...:|||::...|..:|..:|:.|:||:.||::.::|||.|::..|:..||.:.:.|:||..|:
  Fly    12 MCMLVRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEK 76

Human    66 LLKMQNQRGGRALFQDIKKPAEDEWGKTPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFL 130
            ::...|:|||..:...:.:|... :..|.||:|.||.:|.::|:.|||||||.....||:||||:
  Fly    77 IMTYMNKRGGLIILSSVPQPLPC-FASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFI 140

Human   131 ETHFLDEEVKLIKKMGDHLTNLHRLGGPEAGLGEYLFER 169
            |.:||.|:|...|.:.|:::.|.:   .:..:||:||::
  Fly   141 EANFLQEQVDGQKILADYISQLEK---AQNQVGEFLFDK 176

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FTL	NP_000137.2	Ferritin	10..169	CDD:153098	57/158 (36%)
		Catalytic site for iron oxidation	54..61		1/6 (17%)
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	57/157 (36%)