Protein Alignment Pld2 and Pld

DIOPT Version :9

• Sequence 1: XP_038941178.1
• Gene: Pld2 / 25097
• RGDID: 3350
• Length: 972
• Species: Rattus norvegicus
• Sequence 2: NP_001137610.1
• Gene: Pld / 35554
• FlyBaseID: FBgn0286511
• Length: 1364
• Species: Drosophila melanogaster
• Alignment Length: 1243
• Identity: 448/1243 - (36%)
• Similarity: 598/1243 - (48%)
• Gaps: 337/1243 - (27%)

  Rat    24 PDEVDTL------------KEGEDPADRMH-------------PFLAIY--DLQPLRAHPLVFAP 61
            ||.|..|            ||.:|..:...             ||.:||  .::.......||.|
  Fly   165 PDSVTILSNVGDKPVLVERKETDDDEEEFDDEENNSVVLRHEIPFTSIYGPSVKFNSFQRKVFIP 229

  Rat    62 GVPVIAQVVGTERYTSGSKVGTCTLYSVRLTHGDFTWTTKKKFRHFQELH--------------- 111
            |..:..::|.|||..:...:.. .||::.||||.|.||.|::::||..||
  Fly   230 GREIHVRIVDTERSVTTHLLNP-NLYTIELTHGPFKWTIKRRYKHFNSLHQQLSFFRTSLNIPFP 293

  Rat   112 ------------------------RDLQRH-KVLMSLLPL------------------ARFAAAH 133
                                    :||..| ||..:..||                  |..:..|
  Fly   294 SRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSKIAGSNANNAMAMISPNH 358

  Rat   134 S-------PAR------EAANENIPSLP-RGGSEGSARHTASKQKYLENYLNRLLTMSFYRNYHA 184
            |       |.|      :.....:|..| |..|..:..:.:.:.|.||:||..||.:|.||::|.
  Fly   359 SSILAGLTPRRIQKKRKKKKKRKLPRFPNRPESLVTVENLSVRIKQLEDYLYNLLNISLYRSHHE 423

  Rat   185 MTEFLEVSQLSFIPDLGSKGLEGVIRKRSGGHRVPG-----------FTCCGR------DQVCYR 232
            ...|:|||.:||:|.:|.||.||||.||:|..| ||           ..||.|      |.||..
  Fly   424 TLNFVEVSNVSFVPGMGIKGKEGVILKRTGSTR-PGQAGCNFFGCFQKNCCVRCNYFCSDVVCGT 487

  Rat   233 WSKRWLVVKDSFLLYMRPETGAISFVQLFDPGFEVQVGKRSTEARYGVRIDTSHRSLILKCSSYR 297
            |..||..||::...|:||..|:|..|.|||.||:|..|...|..|.|:::.|::|.::|||.:.|
  Fly   488 WRNRWFFVKETCFGYIRPTDGSIRAVILFDQGFDVSTGIYQTGMRKGLQVLTNNRHIVLKCWTRR 552

  Rat   298 QARWWGQEITELAQGPGRDFLQLHQHDSYAPPRPGTLARWFVNGAGYFAAVADAILRAREEIFIT 362
            :.:.|.|.:...|....|||...:.|.|:||.|..|.|.|:|:||.|.:||||.:..|.|||:|.
  Fly   553 KCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADGLEAALEEIYIA 617

  Rat   363 DWWLSPEIYLKRPA-HSDDWRLDIMLKRKAEEGVRVSILLFKEVELALGINSGYSKRTLMLLHPN 426
            |||||||||:|||| ..|.||||.:|.||||:||||.:||:||||:||||||.|||.|| ..|.|
  Fly   618 DWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYYSKSTL-AKHEN 681

  Rat   427 IKVMRHPDL----VTLWAHHEKLLVVDQAVAFLGGLDLAYGRWDDVQYRLTDLG----------- 476
            ||||||||.    :.|||||||::|:||..||:||:||.||||||..:||||||
  Fly   682 IKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLGSISTSSFSGST 746

  Rat   477 ------------------------------------------DPSESADSQTPTPG--------- 490
                                                      :|:.|.:.:|..||
  Fly   747 RRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPSPPPDEPNTSIELKTLKPGDRLLIPSTL 811

  Rat   491 -SDPAATP--------------------------------------DLSH--------------- 501
             |.|..||                                      |..|
  Fly   812 VSSPGETPAESGIALEGMKLNTPEMERKNVLDRLKNNAMKGARMGKDFMHRLTATETEEKSAEVY 876

  Rat   502 ---------------------------------NHF-----FWLGKDYSNLITKDWVQLDRPFEE 528
                                             :.|     :|.||||||.|.|||:.|:.||
  Fly   877 TIESEEATDHEVNLNMASGGQEVAITTSSTQILSEFCGQAKYWFGKDYSNFILKDWMNLNSPF-- 939

  Rat   529 EVRTGTQPEQEPGGLLLPGSFPVDSSVSFLPEPRTTTPDFIDRETTPRMPWRDVGVVVHGVAARD 593
                                                 .|.|||.|||||||.|||:.|.|.:|||
  Fly   940 -------------------------------------VDIIDRTTTPRMPWHDVGLCVVGTSARD 967

  Rat   594 LARHFIQRWNFTKTIKARYKIPQYPYLLPKSASTANHLPFIIPG-AQCATVQVLRSVDRWSAGTL 657
            :|||||||||..|..|.|.. .::|||:|||.......|.|... .|..|.|:||||..||.|.:
  Fly   968 VARHFIQRWNAMKLEKLRDN-TRFPYLMPKSYHQVRLNPNIQQNRQQRVTCQLLRSVSAWSCGFI 1031

  Rat   658 ES-----SILNAYLHTIRESQHFLYIENQFFISCSDG-------RTVLNKVGDEIVDRILKAHEQ 710
            |:     ||.:||:.||.::||::||||||||:...|       ..|.|::|:.:..||::||::
  Fly  1032 EADLVEQSIHDAYIQTITKAQHYVYIENQFFITMQLGMGVPGAYNNVRNQIGETLFKRIVRAHKE 1096

  Rat   711 GQCFRVYVLLPLLPGFEGDISTGGGNSIQAILHFTYRTLCRGEYSILHRLKAAMGTAWRDYMSIC 775
            .:.|||||::|||||||||:....|.:::||.|:.|.::.||..|||.||:.|......:|:|..
  Fly  1097 RKPFRVYVIMPLLPGFEGDVGGSTGIAVRAITHWNYASISRGRTSILTRLQEAGIANPENYISFH 1161

  Rat   776 GLRTHGELGGHPISELIYIHSKLLIADDRTVIIGSANINDRSLLGKRDSELAILIEDTEMEPSLM 840
            .||.|..|...||:||||:||||||||||.||.|||||||||::||||||:|.::.|.|.|...|
  Fly  1162 SLRNHSFLNNTPITELIYVHSKLLIADDRVVICGSANINDRSMIGKRDSEIAAILMDEEFEDGRM 1226

  Rat   841 DGVEYQAGRFALSLRKHCFSVILG-----ANTWPDLDLRDPVCDDFFQ-LWQETAENNATIYEQI 899
            :|.:|.:|.||..|||:.|...||     .::..|||:.||||:.|:. .|:..:..|..||:::
  Fly  1227 NGKKYPSGVFAGRLRKYLFKEHLGLLESEGSSRSDLDINDPVCEKFWHGTWRRISMQNTEIYDEV 1291

  Rat   900 FRCLPSNATRSLRALREYVAVESLATVSPSLAQSELAHIRGHLVHFPLKFLEDESLLPPLGSKEG 964
            |:|:|::..::..:||:|.....||..:|.||.:....|:|:||..||:||..|.|.||..||||
  Fly  1292 FKCIPTDFVKTFASLRKYQEEPPLAKTAPDLAANRANDIQGYLVDLPLEFLNKEVLTPPGTSKEG 1356

  Rat   965 MIPLEVWT 972
            :||..|||
  Fly  1357 LIPTSVWT 1364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pld2	XP_038941178.1	PLN02866	67..957	CDD:215467	422/1156 (37%)
Pld	NP_001137610.1	PX_PLD	230..431	CDD:132805	48/201 (24%)
		PH_PLD	419..564	CDD:269956	57/145 (39%)
		PLDc_vPLD1_2_yPLD_like_1	590..734	CDD:197236	94/144 (65%)
		PLDc_vPLD1_2_yPLD_like_2	1032..1220	CDD:197239	93/187 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166346218
Domainoid	1	1.000	233	1.000	Domainoid score	I2318
eggNOG	1	0.900	-	-		E1_COG1502
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	716	1.000	Inparanoid score	I610
OMA	1	1.010	-	-		QHG58673
OrthoDB	1	1.010	-	-		D330134at33208
OrthoFinder	1	1.000	-	-		FOG0001475
OrthoInspector	1	1.000	-	-		otm45467
orthoMCL	1	0.900	-	-		OOG6_100567
Panther	1	1.100	-	-	O	PTHR18896
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1041
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.810