| Sequence 1: | NP_001036356.1 | Gene: | bru2 / 250811 | FlyBaseID: | FBgn0262475 | Length: | 893 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001340669.1 | Gene: | CELF4 / 56853 | HGNCID: | 14015 | Length: | 545 | Species: | Homo sapiens |
| Alignment Length: | 649 | Identity: | 197/649 - (30%) |
|---|---|---|---|
| Similarity: | 257/649 - (39%) | Gaps: | 238/649 - (36%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 213 ATAAAAAAAAPSTQLNSSINSRTSLGDQGGAIVVVTPAPPVAAPPTGGPNRNQSPTRDCSVKMEL 277
Fly 278 MESTSPDSIKDQPDADNIKMFVGQIPKTWDETRLRQMFEQFGPVHTLNVLRDKVTSISRGCCFVT 342
Fly 343 YYTRKAALRAQDALHNIKTLDGMHHPIQMKPADSENR-----------NERKLFVGMLNKKYTEA 396
Fly 397 DVRQLFTGHGTIEECTVLRDQAGQSKGCAFVTFATKQNAIGAIKALHQSQTMEGCSAPLVVKFAD 461
Fly 462 TQKEKDQKKMQQIHAFCGINTPS----GATAGAATPTINAATALIAAPPSAGRTNPSMAAALAAV 522
Fly 523 PQVQQAGSAATAPTTLVPLNSTTALSASLTPNLLATNAAHQGAAAAAAYLGADPAAAAHLQLYQQ 587
Fly 588 LHGYGLSPAHYLPGLNFHHPPENSAHHSQHSPGIGGASAASLSAAAATAASNPLGGAPPPTPTPT 652
Fly 653 SSAGHAAGAGLLAAPSMSMQNLVALLATPTAHHQLSLHHSSSSSGHNNGNSSATSGLHNQRLTYA 717
Fly 718 AAPPPPPISTTYNMPQLIGHTATPTQPGG--SSQSLTFNALWP-----PNAADPYSSSLSGLTN- 774
Fly 775 ------GAAYGAASQPVTTSALQAAAAGVTGKQIEGPDGSNLFIYHLPQEFIDTDLASTFLPFG 832 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| bru2 | NP_001036356.1 | RRM1_CELF1_2_Bruno | 294..375 | CDD:241075 | 42/80 (53%) |
| RRM2_Bruno_like | 381..461 | CDD:241080 | 49/79 (62%) | ||
| RRM_SF | 801..892 | CDD:302621 | 23/32 (72%) | ||
| CELF4 | NP_001340669.1 | Sufficient for RNA-binding and MSE-dependent splicing activity | 1..298 | 136/328 (41%) | |
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 18..39 | 5/40 (13%) | |||
| RRM1_CELF3_4_5_6 | 49..135 | CDD:241076 | 45/99 (45%) | ||
| PABP-1234 | <56..378 | CDD:130689 | 149/491 (30%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 121..149 | 13/27 (48%) | |||
| RRM2_CELF3_4_5_6 | 151..231 | CDD:241079 | 49/79 (62%) | ||
| Necessary for TNNT2 exon 5 inclusion | 239..258 | 5/18 (28%) | |||
| RRM_SF | 417..>445 | CDD:388407 | 19/27 (70%) |
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C165146321 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0144 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D1209165at2759 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000286 | |
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 1 | 0.900 | - | - | OOG6_100683 | |
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R3223 |
| SonicParanoid | 1 | 1.000 | - | - | X208 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 8 | 7.680 | |||||