Protein Alignment bru2 and Celf2

DIOPT Version :9

• Sequence 1: NP_001036356.1
• Gene: bru2 / 250811
• FlyBaseID: FBgn0262475
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_030103179.1
• Gene: Celf2 / 14007
• MGIID: 1338822
• Length: 536
• Species: Mus musculus
• Alignment Length: 637
• Identity: 265/637 - (41%)
• Similarity: 335/637 - (52%)
• Gaps: 182/637 - (28%)

  Fly   288 DQPDADNIKMFVGQIPKTWDETRLRQMFEQFGPVHTLNVLRDKVTS--ISRGCCFVTYYTRKAAL 350
            ||||.|.|||||||||::|.|..|:::||.:|.|:.:|||||:..:  .|:||||||:|||||||
Mouse    51 DQPDPDAIKMFVGQIPRSWSEKELKELFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAAL 115

  Fly   351 RAQDALHNIKTLDGMHHPIQMKPADSENRN---ERKLFVGMLNKKYTEADVRQLFTGHGTIEECT 412
            .||:||||||||.||||||||||||||..|   :||||:||::||..|.|:|.:|:..|.||||.
Mouse   116 EAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECR 180

  Fly   413 VLRDQAGQSKGCAFVTFATKQNAIGAIKALHQSQTMEGCSAPLVVKFADTQKEKDQKKMQQIHAF 477
            :||...|.|:|||||||:|:..|..||||:||||||||||:|:|||||||||:|:|:::||
Mouse   181 ILRGPDGLSRGCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ---- 241

  Fly   478 CGINTPSGATAGAATPTINAATALIAAPPSAGRTNPSMAAALAAVPQVQQAGSAATAPTTLVPLN 542
                                                      ....|:||..:|.        ..
Mouse   242 ------------------------------------------QLAQQMQQLNTAT--------WG 256

  Fly   543 STTALSASLTPNLLATNAAHQGAAAAAAYLGADPAAAAHLQLYQQLHGYGLSPAHYLPGLNFHHP 607
            :.|.| ..|||..||.    ...|.:::.|||                  .|....:.|:|
Mouse   257 NLTGL-GGLTPQYLAL----LQQATSSSNLGA------------------FSGIQQMAGMN---- 294

  Fly   608 PENSAHHSQHSPGIGGASAASLSAAAATAASNPLGG---------APPPTPTPTSSAGHAAGAGL 663
                |...|:...:..|:||:.::|.:|.| |||..         :|....||.|:||.|
Mouse   295 ----ALQLQNLATLAAAAAAAQTSATSTNA-NPLSSTSSALGALTSPVAASTPNSTAGAA----- 349

  Fly   664 LAAPSMSMQNLVALLATPTAHHQLSLHHSSSSSGHNNGNSSATSGLHNQRLTYAAAPPPPPISTT 728
                   |.:|.:|                   |...|.:.||.||:|..          .::.|
Mouse   350 -------MNSLTSL-------------------GTLQGLAGATVGLNNIN----------ALAGT 378

  Fly   729 YNMPQLIGHTATPTQPGGSSQSLTFNALWPPNAADPYSSSLSGLTNGAA---------------Y 778
            .|:.|::...|...  ||                    ...:|||||.|               |
Mouse   379 INIAQMLSGMAALN--GG--------------------LGATGLTNGTAGTMDALTQAYSGIQQY 421

  Fly   779 GAASQPV--TTSALQAAAAGVTGKQIEGPDGSNLFIYHLPQEFIDTDLASTFLPFGNVLSAKVFI 841
            .||:.|.  :.|.||..:|  .|.|.|||:|:|||||||||||.|.|:...|:|||||:||||||
Mouse   422 AAAALPTLYSQSLLQQQSA--AGSQKEGPEGANLFIYHLPQEFGDQDILQMFMPFGNVISAKVFI 484

  Fly   842 DKQTNLSKCFGFVSYDNPHSANAAIQAMHGFQIGSKRLKVQLKRSKDAAKPY 893
            ||||||||||||||||||.||.||||||:|||||.|||||||||||:.:|||
Mouse   485 DKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 536

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru2	NP_001036356.1	RRM1_CELF1_2_Bruno	294..375	CDD:241075	55/82 (67%)
		RRM2_Bruno_like	381..461	CDD:241080	49/79 (62%)
		RRM_SF	801..892	CDD:302621	72/90 (80%)
Celf2	XP_030103179.1	RRM1_CELF1_2_Bruno	57..140	CDD:241075	55/82 (67%)
		RRM2_CELF1_2	149..229	CDD:241078	49/79 (62%)
		RRM3_CELF1_2	444..535	CDD:241082	72/90 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836406
Domainoid	1	1.000	97	1.000	Domainoid score	I7221
eggNOG	1	0.900	-	-		E1_KOG0144
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4783
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2990
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	11	10.830