Protein Alignment bru2 and celf2

DIOPT Version :9

• Sequence 1: NP_001036356.1
• Gene: bru2 / 250811
• FlyBaseID: FBgn0262475
• Length: 893
• Species: Drosophila melanogaster
• Sequence 2: XP_012813883.1
• Gene: celf2 / 100125022
• XenbaseID: XB-GENE-963640
• Length: 559
• Species: Xenopus tropicalis
• Alignment Length: 644
• Identity: 263/644 - (40%)
• Similarity: 336/644 - (52%)
• Gaps: 184/644 - (28%)

  Fly   288 DQPDADNIKMFVGQIPKTWDETRLRQMFEQFGPVHTLNVLRDKVTS--ISRGCCFVTYYTRKAAL 350
            ||||.|.|||||||||::|.|..|:.:||.:|.|:.:|||||:..:  .|:||||||:|||||||
 Frog    62 DQPDPDAIKMFVGQIPRSWSEKELKDLFEPYGAVYQINVLRDRSQNPPQSKGCCFVTFYTRKAAL 126

  Fly   351 RAQDALHNIKTLDGMHHPIQMKPADSENRN---ERKLFVGMLNKKYTEADVRQLFTGHGTIEECT 412
            .||:||||||||.||||||||||||||..|   :||||:||::||..|.|:|.:|:..|.||||.
 Frog   127 EAQNALHNIKTLPGMHHPIQMKPADSEKSNAVEDRKLFIGMVSKKCNENDIRVMFSPFGQIEECR 191

  Fly   413 VLRDQAGQSKG----CAFVTFATKQNAIGAIKALHQSQTMEGCSAPLVVKFADTQKEKDQKKMQQ 473
            :||...|.|:.    ||||||:|:..|..||||:||||||||||:|:|||||||||:|:|:::||
 Frog   192 ILRGPDGLSRASQHCCAFVTFSTRAMAQNAIKAMHQSQTMEGCSSPIVVKFADTQKDKEQRRLQQ 256

  Fly   474 IHAFCGINTPSGATAGAATPTINAATALIAAPPSAGRTNPSMAAALAAVPQVQQAGSAATAPTTL 538
                                                          ....|:||..:|.
 Frog   257 ----------------------------------------------QLAQQMQQLNTAT------ 269

  Fly   539 VPLNSTTALSASLTPNLLATNAAHQGAAAAAAYLGADPAAAAHLQLYQQLHGYGLSPAHYLPGLN 603
              ..:.|.|.| |||..||.    ...|.:::.|||                  .|....:.|:|
 Frog   270 --WGNLTGLGA-LTPQYLAL----LQQATSSSNLGA------------------FSGIQQMAGMN 309

  Fly   604 FHHPPENSAHHSQHSPGIGGASAASLSAAAATAASNPLG------GAPPPTPTPTSSAGHAAGAG 662
                    |...|:...:..|:||:.::|..|.| |||.      || ..:|...|:|..:|||.
 Frog   310 --------ALQLQNLATLAAAAAAAQTSATTTNA-NPLSTTTSALGA-LTSPVAASTANSSAGAA 364

  Fly   663 LLAAPSMSMQNLVALLATPTAHHQLSLHHSSSSSGHNNGNSSATSGLHNQRLTYAAAPPPPPIST 727
            :                           :|.:|.|...|.:.||.||:|..          .::.
 Frog   365 M---------------------------NSLTSLGTLQGLAGATVGLNNIN----------ALAG 392

  Fly   728 TYNMPQLIGHTATPTQPGGSSQSLTFNALWPPNAADPYSSSLSGLTNGAA--------------- 777
            |.|:.|::...|...  ||                    ...:|||||.|
 Frog   393 TVNIAQMLSGMAALN--GG--------------------LGATGLTNGTAGTMDALTQAYSGIQQ 435

  Fly   778 YGAASQPV--TTSALQAAAAGVTGKQ------IEGPDGSNLFIYHLPQEFIDTDLASTFLPFGNV 834
            |.||:.|.  :.|.||..:|..:.|:      .:||:|:|||||||||||.|.|:...|:|||||
 Frog   436 YAAAALPTLYSQSLLQQQSAAGSQKEGLLFISSQGPEGANLFIYHLPQEFGDQDILQMFMPFGNV 500

  Fly   835 LSAKVFIDKQTNLSKCFGFVSYDNPHSANAAIQAMHGFQIGSKRLKVQLKRSKDAAKPY 893
            :||||||||||||||||||||||||.||.||||||:|||||.|||||||||||:.:|||
 Frog   501 ISAKVFIDKQTNLSKCFGFVSYDNPVSAQAAIQAMNGFQIGMKRLKVQLKRSKNDSKPY 559

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bru2	NP_001036356.1	RRM1_CELF1_2_Bruno	294..375	CDD:241075	55/82 (67%)
		RRM2_Bruno_like	381..461	CDD:241080	48/83 (58%)
		RRM_SF	801..892	CDD:302621	70/96 (73%)
celf2	XP_012813883.1	RRM1_CELF1_2_Bruno	68..151	CDD:241075	55/82 (67%)
		ELAV_HUD_SF	71..554	CDD:273741	252/628 (40%)
		RRM2_CELF1_2	160..244	CDD:241078	48/83 (58%)
		RRM3_CELF1_2	469..558	CDD:241082	70/88 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7190
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H4783
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1209165at2759
OrthoFinder	1	1.000	-	-		FOG0000286
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24012
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2990
SonicParanoid	1	1.000	-	-		X208
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.050