Protein Alignment bwa and ACER3

DIOPT Version :10

• Sequence 1: NP_001260616.1
• Gene: bwa / 250736
• FlyBaseID: FBgn0045064
• Length: 300
• Species: Drosophila melanogaster
• Sequence 2: NP_060837.3
• Gene: ACER3 / 55331
• HGNCID: 16066
• Length: 267
• Species: Homo sapiens
• Alignment Length: 278
• Identity: 85/278 - (30%)
• Similarity: 126/278 - (45%)
• Gaps: 67/278 - (24%)

  Fly    22 PGSSPVDWCEGNYLISSNIAEFVNTFSNFLFILLPPVLIMLFKEYG--RFVTPGIH----VIWVL 80
            |.:|.:||||.||.::..||||.||.|| |.:::||:       :|  :.|..|:.    ..::.
Human    13 PTTSTLDWCEENYSVTWYIAEFWNTVSN-LIMIIPPM-------FGAVQSVRDGLEKRYIASYLA 69

  Fly    81 LIVVGLSSMYFHATLSLIGQLLDELAILW---VFM-AAFSLFYPK---RYYPKFVKNDRKTFSWL 138
            |.|||:.|..||.||....||||||.:::   :|: ..|..|..|   .|:..|.         |
Human    70 LTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKIKNSVNYHLLFT---------L 125

  Fly   139 MLLSAIAAT-GLSWWKPIVN-------AFVLMFMSVPTMVMLYTELQRVSDQRVYRLGIRSTTVW 195
            :|.|.|..| .|...:||.:       .|.|:..|:..:..:|..|:        .||..|..::
Human   126 VLFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLR--------GLGYTSLGIF 182

  Fly   196 AVAVFCWINDRIFCEAWSSINF-----PYL------HGFWHIFIFIAAYTVLVLFAYFYVESELP 249
            .:....|..|.||||  |..||     |.:      |.:|||...:.:| :.:||:.:
Human   183 LLGFLFWNIDNIFCE--SLRNFRKKVPPIIGITTQFHAWWHILTGLGSY-LHILFSLY------- 237

  Fly   250 QRQPLLKYWPKNEFEFGI 267
            .|...|:|.||.:|.|||
Human   238 TRTLYLRYRPKVKFLFGI 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bwa	NP_001260616.1	Ceramidase	22..271	CDD:461766	85/278 (31%)
ACER3	NP_060837.3	Ceramidase	12..263	CDD:461766	85/278 (31%)