DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fdl and HEXO2

DIOPT Version :9

Sequence 1:	NP_725178.2	Gene:	fdl / 250735	FlyBaseID:	FBgn0045063	Length:	673	Species:	Drosophila melanogaster
Sequence 2:	NP_001318927.1	Gene:	HEXO2 / 837064	AraportID:	AT1G05590	Length:	580	Species:	Arabidopsis thaliana

Alignment Length:	617	Identity:	187/617 - (30%)
Similarity:	291/617 - (47%)	Gaps:	129/617 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   108 VNIWPHPTQKFLLSSQTHSFSVEDVQLHVDTAHREVRKQLQLAFDWFLKDLRLIQRLDYVGSSSE 172
            :||||.|  :||...|                    .|.:.|:.::.:    |.....|:
plant    31 INIWPKP--RFLSWPQ--------------------HKAIALSPNFTI----LAPEHQYL----- 64

  Fly   173 PTVSESSSKSRHHADL--EPAATLFGATFGVKKAGDLTSVQVKISVLKSGDLNFSLDN--DETYQ 233
                 |:|.:|:|..:  |..:.|......:.|...|.::.|.::     |.:..|.:  ||:|:
plant    65 -----SASVTRYHNLIRSENYSPLISYPVKLMKRYTLRNLVVTVT-----DFSLPLHHGVDESYK 119

  Fly   234 LSTQTEGHRLQVEIIANSYFGARHGLSTLQQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDT 298
            ||.....  ....::|:|.:||..||.|..|:||....|..|.  ....::|:|.|.:||::|||
plant   120 LSIPIGS--FSAHLLAHSAWGAMRGLETFSQMIWGTSPDLCLP--VGIYIQDSPLFGHRGVLLDT 180

  Fly   299 SRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHGAYSESETYSEQDVREV 363
            ||:::.|:.|.|||..|...|:|.||||:||:||||.:....|.||..|:......|:.:||.::
plant   181 SRNYYGVDDIMRTIKAMSANKLNVFHWHITDSQSFPLVLPSEPSLAAKGSLGPDMVYTPEDVSKI 245

  Fly   364 AEFAKIYGVQVIPEIDAPAHAGNGWDWGPKRGMGELAMCINQQPW-------SFYCGEPPCGQLN 421
            .::...:||:|:||||.|.|.|:   ||  ....|:..|.|...|       .....||..||||
plant   246 VQYGFEHGVRVLPEIDTPGHTGS---WG--EAYPEIVTCANMFWWPAGKSWEERLASEPGTGQLN 305

  Fly   422 PKNNYTYLILQRIYEELLQHTGPTDFFHLGGDEVNLDCW--------------------AQYFND 466
            |.:..||.:::.:.::::... |..|||.|||||...||                    .:|.|.
plant   306 PLSPKTYEVVKNVIQDIVNQF-PESFFHGGGDEVIPGCWKTDPAINSFLSSGGTLSQLLEKYINS 369

  Fly   467 T------DLRGL--WCDFMLQAMARLKLANNGVAPKH---VAVWSSALTNTKCLPNSQFTVQVWG 520
            |      ..|.:  |.|.:|.|..:   |:..|.||.   :..|::...|||
plant   370 TLPYIVSQNRTVVYWEDVLLDAQIK---ADPSVLPKEHTILQTWNNGPENTK------------- 418

  Fly   521 GSTWQENYDLLDNGYNVIFSHVDAWYLDCGFGSW----------RATGDAACAPYRTWQNVYKHR 575
                    .::..||.||.|..:.:|||||.|.:          .:.|.:.|||::|||::|.:.
plant   419 --------RIVAAGYRVIVSSSEFYYLDCGHGGFLGNDSIYDQKESGGGSWCAPFKTWQSIYNYD 475

  Fly   576 PWERMRLDKKRKKQVLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDMDIVPPDVF 640
            ..:.: |:::.:|.||||||.:|:||.|...||:|||||.:||||.||:...|:..:... .:..
plant   476 IADGL-LNEEERKLVLGGEVALWSEQADSTVLDSRLWPRASALAESLWSGNRDERGVKRC-GEAV 538

  Fly   641 RRISLFRNRLVELGIRAEALFPKYCAQNPGEC 672
            .|::|:|.|:|:.||.||.:.|.:|.:|||.|
plant   539 DRLNLWRYRMVKRGIGAEPIQPLWCLKNPGMC 570

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fdl	NP_725178.2	Glycohydro_20b2	110..265	CDD:291511	34/158 (22%)
fdl	NP_725178.2	GH20_HexA_HexB-like	289..654	CDD:119332	135/412 (33%)
HEXO2	NP_001318927.1	Glycohydro_20b2	33..149	CDD:373334	34/158 (22%)
HEXO2	NP_001318927.1	GH20_HexA_HexB-like	171..552	CDD:119332	135/412 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	232	1.000	Domainoid score	I643
eggNOG	1	0.900	-	-		E1_COG3525
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	283	1.000	Inparanoid score	I864
OMA	1	1.010	-	-		QHG54329
OrthoDB	1	1.010	-	-		D545162at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3150
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22600
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X846
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.980