Protein Alignment fdl and Hexb

DIOPT Version :10

• Sequence 1: NP_725178.2
• Gene: fdl / 250735
• FlyBaseID: FBgn0045063
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_001011946.1
• Gene: Hexb / 294673
• RGDID: 1307607
• Length: 537
• Species: Rattus norvegicus
• Alignment Length: 553
• Identity: 171/553 - (30%)
• Similarity: 251/553 - (45%)
• Gaps: 105/553 - (18%)

  Fly   156 KDLRLIQRLDYVG-------SSSEPTVSESSS----------------KSRHHADLEPAATLFGA 197
            :.:::..||.|:.       :|...|...|.|                ..|||..         |
  Rat    39 RSVQVFPRLLYISPENFQIDNSPNSTAGPSCSLLLEAFRRYYNYIFGFYKRHHGP---------A 94

  Fly   198 TFGVKKAGDLTSVQVKISVLKSGDLNFSLDNDETYQLSTQTEGHRLQVEIIANSYFGARHGLSTL 262
            .|..|.  .|..:.|.|::....|...|:.:||:|.|..|.....|:    ||..:||..||.|.
  Rat    95 KFQDKP--QLEKLLVFINLEPQCDAFPSMSSDESYSLLVQEPVALLK----ANEVWGALRGLETF 153

  Fly   263 QQLIWFDDEDHLLHTYANSKVKDAPKFRYRGLMLDTSRHFFSVESIKRTIVGMGLAKMNRFHWHL 327
            .||::.|  .:...|...|.:.|:|:|.:||:::|||||:..|::|.:|:..|...|.|..|||:
  Rat   154 SQLVYQD--AYGTFTINESTIADSPRFPHRGILIDTSRHYLPVKTIFKTLDAMAFNKFNVLHWHI 216

  Fly   328 TDAQSFPYISRYYPELAVHGAYSESETYSEQDVREVAEFAKIYGVQVIPEIDAPAHAGNGWDWGP 392
            .|.|||||.|..:|||:..|:||.|..|:..|:..|.|:|::.|::||||.|:|.|. ..|..|.
  Rat   217 VDDQSFPYQSITFPELSNKGSYSLSHVYTPNDIHMVLEYARLRGIRVIPEFDSPGHT-QSWGKGQ 280

  Fly   393 KRGMGELAMCINQQPWSFYCGEPPCGQLNPKNNYTYLILQRIYEELLQHTGPTDFFHLGGDEVNL 457
            |   ..|..|..|:     ......|.::|..|.||:.....::| :....|..|.|||||||..
  Rat   281 K---NLLTPCFIQK-----IRTQKVGPVDPSLNTTYVFFDTFFKE-ISRVFPDQFIHLGGDEVEF 336

  Fly   458 DCWA-----QYF--------NDTDLRGLWCDFMLQAMARLKLANNGVAPKHVAVWSSALTN-TKC 508
            :|||     |.|        |...|...:...:|..:..||        |...||.....: .:.
  Rat   337 ECWASNPNIQNFMKKKGFGNNFRRLESFYIKKILDIITSLK--------KSSIVWQDVFDDQVEL 393

  Fly   509 LPNSQFTVQVWGGSTWQENY-----DLLDNGYNVIFSHVDAWYLD-CGFGSWRATGDAACAPYRT 567
            .|.:  .|:||.    .|||     .:..:|:..|.|  ..|||| ..:|             :.
  Rat   394 QPGT--VVEVWK----SENYLNELAQVTASGFPAILS--APWYLDLISYG-------------QD 437

  Fly   568 WQNVYKHRPWERMRLDKKRKKQVLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDM 632
            |:|.||..|. .....:|:|:.|:|||.|:|.|.||...|..|||||.:|:.||||: |....::
  Rat   438 WRNYYKAEPL-NFEGSEKQKQLVIGGEACLWGEYVDATNLIPRLWPRASAVGERLWS-PRIITNL 500

  Fly   633 DIVPPDVFRRISLFRNRLVELGIRAEALFPKYC 665
            :    :.:||:::.|.|:|..||.|:.||..||
  Rat   501 E----NAYRRLAVHRCRMVSRGIAAQPLFTGYC 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fdl	NP_725178.2	Glycohydro_20b2	110..265	CDD:434261	31/131 (24%)
		GH20_HexA_HexB-like	289..654	CDD:119332	126/384 (33%)
Hexb	NP_001011946.1	Glycohydro_20b2	34..156	CDD:434261	31/131 (24%)
		GH20_HexA_HexB-like	178..518	CDD:119332	126/384 (33%)