Protein Alignment fdl and hex-1

DIOPT Version :10

• Sequence 1: NP_725178.2
• Gene: fdl / 250735
• FlyBaseID: FBgn0045063
• Length: 673
• Species: Drosophila melanogaster
• Sequence 2: NP_508409.1
• Gene: hex-1 / 180533
• WormBaseID: WBGene00020509
• Length: 555
• Species: Caenorhabditis elegans
• Alignment Length: 467
• Identity: 141/467 - (30%)
• Similarity: 221/467 - (47%)
• Gaps: 79/467 - (16%)

  Fly   238 TEGHRLQVE-----IIANSYFGARHGLSTLQQLIWFD--DEDHLLHTYANSKVKDAPKFRYRGLM 295
            :|.:.|:|.     |.|.:.:||...:.:|..|:::|  .:::.:.|.   ::.|.|:|..||:|
 Worm   115 SEEYLLRVSLTEAVINAQTVWGALRAMESLSHLVFYDHKSQEYQIRTV---EIFDKPRFPVRGIM 176

  Fly   296 LDTSRHFFSVESIKRTIVGMGLAKMNRFHWHLTDAQSFPYISRYYPELAVHGAYSESETYSEQDV 360
            :|:||||.||..|||.:..|.:.|:|..||||.|::||||.|..:|||...||||....||.:|:
 Worm   177 IDSSRHFLSVNVIKRQLEIMSMNKLNVLHWHLVDSESFPYTSVKFPELHGVGAYSPRHVYSREDI 241

  Fly   361 REVAEFAKIYGVQVIPEIDAPAHAGNGWDWGPKRGMGELAMCINQQPWSFYCGEPPCGQLNPKNN 425
            .:|..||::.|::||||.|.|.|..:   |..::|.  |..|.:::....:..    ..::|.|.
 Worm   242 ADVIAFARLRGIRVIPEFDLPGHTSS---WRGRKGF--LTECFDEKGVETFLP----NLVDPMNE 297

  Fly   426 YTYLILQRIYEELLQHTGPTDFFHLGGDEVN---LDCWAQ------------YFNDTD-LRGLWC 474
            ..:..:....||:.: |.|..|.|||||||:   ::||.:            :.|||. |...:.
 Worm   298 ANFDFISEFLEEVTE-TFPDQFLHLGGDEVSDYIVECWERNKKIRKFMEEKGFGNDTVLLENYFF 361

  Fly   475 DFMLQAMARLKLANNGVAPKHVAVWSSALTNTKCLPNSQFTVQVWGGSTWQENYDLLDN----GY 535
            :.:.:.:..|||....:      .|.....|.  :|:....:.:|.|:|.:|.|:.:.|    .:
 Worm   362 EKLYKIVENLKLKRKPI------FWQEVFDNN--IPDPNAVIHIWKGNTHEEIYEQVKNITSQNF 418

  Fly   536 NVIFSHVDAWYLD-CGFGS-WR--ATGDAA-------CAPYRTWQNVYKHRPWERMRLDKKRKKQ 589
            .||.|  ..|||: ..:|: ||  ..|.|.       |.|......|             .:|:.
 Worm   419 PVIVS--ACWYLNYIKYGADWRDEIRGTAPSNSRYYYCDPTNFNGTV-------------AQKEL 468

  Fly   590 VLGGEVCMWTEQVDENQLDNRLWPRTAALAERLWTDPSDDHDMDIVPPDVFRRISLFRNRLVELG 654
            |.||...:|.|.||...::.|||||.:|.|||||:........:    |.:.|:...|.|||..|
 Worm   469 VWGGIAAIWGELVDNTNIEARLWPRASAAAERLWSPAEKTQRAE----DAWPRMHELRCRLVSRG 529

  Fly   655 IRAEA-LFPKYC 665
            .|.:. ..|.||
 Worm   530 YRIQPNNNPDYC 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fdl	NP_725178.2	Glycohydro_20b2	110..265	CDD:434261	8/31 (26%)
		GH20_HexA_HexB-like	289..654	CDD:119332	123/395 (31%)
hex-1	NP_508409.1	Glyco_hydro_20b	34..147	CDD:446174	8/31 (26%)
		GH20_HexA_HexB-like	170..529	CDD:119332	123/395 (31%)