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Protein Alignment Hk2 and Hex-A

DIOPT Version :9

Sequence 1:	NP_036867.1	Gene:	Hk2 / 25059	RGDID:	2797	Length:	917	Species:	Rattus norvegicus
Sequence 2:	NP_524848.1	Gene:	Hex-A / 45875	FlyBaseID:	FBgn0001186	Length:	541	Species:	Drosophila melanogaster

Alignment Length:	447	Identity:	227/447 - (50%)
Similarity:	301/447 - (67%)	Gaps:	14/447 - (3%)

- Green bases have known domain annotations that are detailed below.

  Rat    22 VDQFLYHMRLSDETLLEISRRFRKEMEKGLGATTHPTAAVKMLPTFVRSTPDGTEHGEFLALDLG 86
            |.:....:.|:||.:.|:..|...|:.:||...|||.|.||...|:|:..|:|.|.|:|||||||
  Fly    95 VHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFLALDLG 159

  Rat    87 GTNFRVLRVRVTDNGLQRVEMENQIYAIPEDIMRGSGTQLFDHIAECLANFMDKLQIKEKKLPLG 151
            |||||||.:.:.:|  ...:||::|||||:.||.||||||||||||||:|||.:..:.:::||||
  Fly   160 GTNFRVLLIHLQEN--NDFQMESRIYAIPQHIMIGSGTQLFDHIAECLSNFMAEHNVYKERLPLG 222

  Rat   152 FTFSFPCHQTKLDESFLVSWTKGFKSSGVEGRDVVDLIRKAIQRRGDFDIDIVAVVNDTVGTMMT 216
            ||||||..|..|.:..|.:|||||..:||...|||.|::.||.||||..||:.|::|||.||:|:
  Fly   223 FTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDVCAILNDTTGTLMS 287

  Rat   217 CGYDDQNCEIGLIVGTGSNACYMEEMRHIDMVEGDEGR---MCINMEWGAFGDDGTLNDIRTEFD 278
            |.:.:.||:||||||||:||||||.:...::...::.|   :.||.|||||||:|.|:.:|||||
  Fly   288 CAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKHVLINTEWGAFGDNGALDFVRTEFD 352

  Rat   279 REIDMGSLNPGKQLFEKMISGMYMGELVRLILVKMAKAELLFQGKLSPELLTTGSFETKDVSDIE 343
            |:||:.|:|||||.||||||||||||||||:||||.:|.:||.|:.|..|.|.|.|.||.||:||
  Fly   353 RDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILFNGQDSEVLNTRGLFFTKYVSEIE 417

  Rat   344 EDKDG-IEKAYQILMRLGL-NPLQEDCVATHRICQIVSTRSASLCAATLAAVLWRIKENKGEERL 406
            .|:.| ......:|..||| |....||.....||:.||.|:|.|.:|.:|.::     ||.:|.
  Fly   418 ADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECVSKRAAHLVSAGIATLI-----NKMDEP- 476

  Rat   407 RSTIGVDGSVYKKHPHFAKRLHKAVRRLV-PDCDVRFLRSEDGSGKGAAMVTAVAYR 462
            ..|:|||||||:.||.|...:.:.:.:|: |......:.||||||:|||:|.|||.|
  Fly   477 TVTVGVDGSVYRFHPKFHNLMVEKISQLIKPGITFDLMLSEDGSGRGAALVAAVACR 533

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.