DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lipa and mag

DIOPT Version :9

Sequence 1:	NP_036864.3	Gene:	Lipa / 25055	RGDID:	3008	Length:	397	Species:	Rattus norvegicus
Sequence 2:	NP_649229.1	Gene:	mag / 40267	FlyBaseID:	FBgn0036996	Length:	399	Species:	Drosophila melanogaster

Alignment Length:	398	Identity:	134/398 - (33%)
Similarity:	207/398 - (52%)	Gaps:	24/398 - (6%)

- Green bases have known domain annotations that are detailed below.

  Rat    11 VVGILLSGGPTGTISAVDPEANMNVTEIIMHWGYPGEEHSVQTGDGYILGVHRIP--HGRKNQFD 73
            |.|::|:......:|.:     :...|.|...|||.|.|.|.|.|||:|.:.|||  |..|||.:
  Fly    13 VAGLVLAEKSDYCLSEI-----VKSDERIRSHGYPTETHEVTTQDGYVLTLFRIPYSHKLKNQNE 72

  Rat    74 KGPKPVVYLQHGFLADSSNWVTNIDNNSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQDEYW 138
            |  :|.:.||||..::|..|:::..:|||.::|||||:|||:||:|||.:||.:..:|::..::|
  Fly    73 K--RPPILLQHGLFSNSDCWLSSGPDNSLAYLLADAGYDVWLGNARGNIYSRNNIIISLNSHKFW 135

  Rat   139 AFSFDEMAKYDLPASINYILNKTGQEQLYYVGHSQGCTIGFIAFSQMPELAKKVKMFFALAPV-- 201
            .|.:.|:...|:||.|:|||..||.:|::|.|||||.|:..:..|:.||....:|....|||.
  Fly   136 HFDWHEIGTIDIPAMIDYILADTGFDQIHYAGHSQGTTVYLVMLSERPEYNALIKSGHLLAPCAF 200

  Rat   202 ----LSLNF-ASGPMVKLGRLPDLLLEDLFGQKQFLPQSAMVKWLSTHICTHVIMKELCANIFFL 261
                .|..| |.||:|   ..|..:...|....:.:|.:.:|..|..:.| | :...:|.|.|.:
  Fly   201 FEHGTSFIFNALGPLV---GTPGGIWNQLLVDTELIPNNNLVNRLVDNSC-H-LSNTICNNAFIM 260

  Rat   262 ICGFNEKNLNMSRVDVYTTHCPAGTSVQNMVHWTQVVKYHKLQAFDWGSSDKNYFHYNQSYPPLY 326
            .......|.|.|.:.|.....|||:|....:|:.|:.|..|.:.:|||:. ||...|.|..||.|
  Fly   261 FANGGYVNANASSMSVLIETHPAGSSSNQGIHYLQLWKSLKFRQYDWGTK-KNNELYGQDLPPDY 324

  Rat   327 SIKDMQLPTALWSGGKDWLADTSDINILLTEIPTLV--YHKNIPEWDHLDFIWGLDAPWRLYNEV 389
            .:..:..||.|:|...|.|....|:|.|:...|.|.  |...:..::|||||...:....:.:.:
  Fly   325 DLSKIVAPTHLYSSTNDALCGPEDVNTLVENFPHLTEDYRVPVQSFNHLDFIIAKNMKELVNDPI 389

  Rat   390 VSLMKKYQ 397
            :..:..|:
  Fly   390 IERINSYE 397

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lipa	NP_036864.3	PLN02872	7..394	CDD:215470	133/393 (34%)
		Abhydro_lipase	35..96	CDD:282003	28/62 (45%)
		Abhydrolase_5	78..>203	CDD:289465	53/130 (41%)
mag	NP_649229.1	Abhydro_lipase	34..94	CDD:282003	28/61 (46%)
		MhpC	56..366	CDD:223669	112/317 (35%)
		Abhydrolase_5	76..>197	CDD:289465	50/120 (42%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335497
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2624
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	272	1.000	Inparanoid score	I2916
OMA	1	1.010	-	-		QHG55134
OrthoDB	1	1.010	-	-		D408561at33208
OrthoFinder	1	1.000	-	-		FOG0000083
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11005
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X80
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	10	9.910