DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Vars1 and GstE13

DIOPT Version :9

Sequence 1:	NP_445744.1	Gene:	Vars1 / 25009	RGDID:	3950	Length:	1264	Species:	Rattus norvegicus
Sequence 2:	NP_001188889.1	Gene:	GstE13 / 35928	FlyBaseID:	FBgn0033381	Length:	226	Species:	Drosophila melanogaster

Alignment Length:	179	Identity:	42/179 - (23%)
Similarity:	66/179 - (36%)	Gaps:	52/179 - (29%)

- Green bases have known domain annotations that are detailed below.

  Rat   574 PIVF--DDFVDMEFGTGAVKITPAHD-----QNDYEVGQRHRLEAISIMDSKGALVNVPPPFLG- 630
            |:.|  .:.:..||    ||:.|.|.     .:|.||          .:||...:..:...:.|
  Fly    33 PVDFAKKEHLSEEF----VKLNPQHQIPVFVDSDGEV----------YVDSHAIVCFLVAKYAGN 83

  Rat   631 ---LPRFEARKAVL--AALKEQG-LFRGIKD-------------NPMVVPLCNRSKDVVEPLLRP 676
               .||...|:|.:  ....|.| ||:.:||             ||..:.||:.:...:|..|:.
  Fly    84 DQLYPRDLKRRAHIDHRMHYENGVLFQVVKDIVARNIYGGEGEYNPRSLTLCHNAYSDLEHFLQQ 148

  Rat   677 QWYVRCGEMAQA-ASAAVTRGDLRIL--------PEAHQRTWHSWMDNI 716
            ..:|...|::.| .|...|...|.:|        |:..|  |...||.:
  Fly   149 GSFVVGNELSVADVSIHTTLVTLDLLIPVEREKYPQTKQ--WMERMDKL 195

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Vars1	NP_445744.1	GstA	<56..203	CDD:223698
		GST_C_family	92..213	CDD:295467
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	218..296
		PTZ00419	282..1264	CDD:240411	42/179 (23%)
		ValRS_core	335..938	CDD:185677	42/179 (23%)
		'HIGH' region	344..354
		tRNA-synt_1_2	513..640	CDD:290334	17/76 (22%)
		'KMSKS' region	862..866
		Anticodon_Ia_Val	938..1075	CDD:153416
		Val_tRNA-synt_C	1196..1258	CDD:287436
GstE13	NP_001188889.1	GST_N_Delta_Epsilon	4..78	CDD:239343	13/58 (22%)
GstE13	NP_001188889.1	GST_C_Delta_Epsilon	92..211	CDD:198287	26/106 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0625
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810