DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ABL1 and LSB1

DIOPT Version :9

Sequence 1:	NP_009297.2	Gene:	ABL1 / 25	HGNCID:	76	Length:	1149	Species:	Homo sapiens
Sequence 2:	NP_011652.1	Gene:	LSB1 / 853037	SGDID:	S000003368	Length:	241	Species:	Saccharomyces cerevisiae

Alignment Length:	122	Identity:	33/122 - (27%)
Similarity:	53/122 - (43%)	Gaps:	18/122 - (14%)

- Green bases have known domain annotations that are detailed below.

Human    66 RWNSKENLLAGPSENDPNLFV-ALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGW 129
            :|:..:.   .|...|...:| |||||.|..|..||:..|:|::|| ...:.:|...::.|..|.
Yeast    41 KWDGNQR---SPQNADTEEYVEALYDFEAQQDGDLSLKTGDKIQVL-EKISPDWYRGKSNNKIGI 101

Human   130 VPSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRY 186
            .|:||:.|.        :....|..:||...||.::     |.|...|.....:.:|
Yeast   102 FPANYVKPA--------FTRSASPKSAEAASSSTVS-----RPSVPPPSYEPAASQY 145

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ABL1	NP_009297.2	SH3_Abl	84..137	CDD:212784	20/53 (38%)
		SH2_ABL	142..235	CDD:198189	9/45 (20%)
		PTKc_Abl	254..516	CDD:270645
		Pkinase_Tyr	261..512	CDD:285015
		FABD	1025..1149	CDD:197885
LSB1	NP_011652.1	SH3	55..108	CDD:214620	20/53 (38%)
LSB1	NP_011652.1	PRK14971	<100..>156	CDD:237874	14/59 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000006
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000