Protein Alignment hoe1 and PHO90

DIOPT Version :9

• Sequence 1: NP_001285607.1
• Gene: hoe1 / 249663
• FlyBaseID: FBgn0041150
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: NP_012337.1
• Gene: PHO90 / 853241
• SGDID: S000003734
• Length: 881
• Species: Saccharomyces cerevisiae
• Alignment Length: 881
• Identity: 166/881 - (18%)
• Similarity: 297/881 - (33%)
• Gaps: 271/881 - (30%)

  Fly    18 TRDPYHLQPGDDDDDRDEDE--ERQTKLQEIISWLH---LNAKHRSKCEVTEGALQVWRTLPERI 77
            |.|  .:.|.|.|||.|:||  :.|:.:::..:.||   .|.|.:.|..:.:..:.::..|.:
Yeast   195 TND--EVPPLDLDDDEDDDEFYDDQSNIEDNTALLHHSQYNIKSQKKSLLKKSIVNLYIDLCQ-- 255

  Fly    78 RQDPSLASFRQ--------------------------EHERLHGDVDQLHAEESELRVQNGHHEE 116
                 |.||.:                          |.|:...|.....||..||
Yeast   256 -----LKSFIELNRIGFAKITKKSDKVLHLNTRTELIESEQFFKDTYAFQAETIEL--------- 306

  Fly   117 TALANQPFTQIGINVTNEAGQVRVLDGRDLENNNDDQHDEAEPHAKSLIRKYLIWFKIAILLVVW 181
                          :.::..|:.....|..:..::..|.:.|  .||.:..:::|.:
Yeast   307 --------------LNSKISQLVTFYARITDRPHNISHSKQE--LKSYLHDHIVWER-------- 347

  Fly   182 CVFTAFLMSNNEHVDQLSLISVPRNSSPRVFP------IATASLQRIGLGLRGPFRLQENELAIN 240
                     :|...|.|.|:|.....:|:...      :....|:.....|..|..|:..  :||
Yeast   348 ---------SNTWKDMLGLLSQADELTPKETEYNANKLVGKLDLEYYRWPLPRPINLKFT--SIN 401

  Fly   241 ASVPLPLLQVQVMRSYFDGEGMEIYIENASQVWQLDVVYPDL---IDATRDTKKQRTFELSPTDP 302
             :|.||.|       :|..:..:||         ..::...|   |....|..:.|...|.....
Yeast   402 -NVALPKL-------FFTKKAYKIY---------FIILVTGLLLGIKTFNDAAQHRCMALVECVA 449

  Fly   303 -LWLAQANRTELSFEFTSSIEGELPLQLNVDESPIYKRDGVIYAAAVLCGLYVMIIWEIVNRTFA 366
             ||.::|                :||.:.....|:                 ::::::::..:..
Yeast   450 FLWASEA----------------IPLHITAFLVPL-----------------LVVLFKVLKTSDG 481

  Fly   367 AII-ASTLSVGILAALNSRPSMATIMGWIDVETLLLLFGMMILVAILSETGVFDYLAVYAYKITN 430
            ||: |::.|..||||:.|             .|:::|.....|..:|::..:...||.:......
Yeast   482 AIMSAASASSEILAAMWS-------------STIMILLAGFTLGEVLAQYNIAKVLASWLLAFAG 533

  Fly   431 ---GHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVTIRLCEVMCLNPVPILMCMV----IYSNI 488
               .:|..:..|:..|   ||.::.||...:|...:...|.:.|..:. |....:|    :.:||
Yeast   534 CKPRNVLLMAMCVVFF---LSMWISNVAAPVLTYSLLSPLLDAMDADS-PFAQALVLGVALAANI 594

  Fly   489 GGALTPVGDPPNVIIASNSYISKNGVNFAVFTLHMLPGVLLVMVQTYIQLRFKFRNISDLQFKDS 553
            ||..:|:..|.|:|  |.||:...|:.:..|....||..:|.|:..:|.|...|
Yeast   595 GGMSSPISSPQNII--SMSYLKPYGIGWGQFFAVALPSGILAMLLVWILLFTTF----------- 646

  Fly   554 PEVEELRHEIHVWKRAAASLSAYSKDEELVRQTLMKKVNRLKRSLKKRMTAVIEPAPNYQQTLAN 618
                                                |:|:.|
Yeast   647 ------------------------------------KMNKTK----------------------- 652

  Fly   619 LQAKYPIRNKPLLIKCSAALVFVISLFFLHSVPELQRLSLGWTALLGAIFLII-----LADIEDM 678
            |:...||:.| ..:|....:...::...|..|......:.|.:..:..|.:::     |...:|:
Yeast   653 LEKFKPIKTK-FTVKQYYIITVTVATILLWCVESQIEGAFGSSGQIAIIPIVLFFGTGLLSTQDL 716

  Fly   679 EAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGVGEDRRLMVAILIILWV-SAV 742
            .|.    .||.::.......|.:|::..||:..|....:..|...|     :.|||.|..: ..|
Yeast   717 NAF----PWSIVILAMGGIALGKAVSSSGLLSTIAKALQKKIENDG-----VFAILCIFGILMLV 772

  Fly   743 ASAFVDNIPLTTMMVKITISLAQ---NSTLNLPLQP-LVWALA-LGACLGGNGTLIGASANVVCA 802
            ...||.:    |:...|.|.|.|   :...|....| ||:..| |.:|  |.|.......||...
Yeast   773 VGTFVSH----TVSAIIIIPLVQEVGDKLGNPKAAPILVFGCALLSSC--GMGLASSGFPNVTAI 831

  Fly   803 GVAEQHGYKF-TFLQFFKVGFP--IMIGSIIVTTGY 835
            ...::.|.:: :.:.|...|.|  |:....::|.||
Yeast   832 SKVDRKGDRYLSVMTFLTRGVPASILAFLCVITLGY 867

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hoe1	NP_001285607.1	ArsB	345..839	CDD:223983	102/513 (20%)
		P_permease	349..837	CDD:238536	102/509 (20%)
PHO90	NP_012337.1	COG5408	1..288	CDD:227695	20/101 (20%)
		SLC13_permease	442..870	CDD:238535	109/564 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157343707
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930