Protein Alignment hoe1 and oca2

DIOPT Version :10

• Sequence 1: NP_608876.1
• Gene: hoe1 / 249663
• FlyBaseID: FBgn0041150
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_021332872.2
• Gene: oca2 / 567419
• ZFINID: ZDB-GENE-070718-4
• Length: 834
• Species: Danio rerio
• Alignment Length: 845
• Identity: 333/845 - (39%)
• Similarity: 482/845 - (57%)
• Gaps: 123/845 - (14%)

  Fly    87 RQEHERLHGDVDQLHAEESELRVQNGHHEETAL---ANQP------FTQIGINVTNEAGQVRVLD 142
            |::.:.:.|:.|:|...|.    .:|..|...|   |..|      :|.:.....:....|.:|:
Zfish    27 RRKSDSVSGNFDELRLLEG----FSGKKETQKLLQAAAMPSGHCIIYTDVHQEDRHSFNMVNLLN 87

  Fly   143 GRDLENNNDDQHDEAEP---------------HAKSLIRKYLIWFKIAILLVVWCVFTAFLMSNN 192
            |:    :|...|.|..|               |..||......|...:..|...|..       .
Zfish    88 GK----SNQANHTERTPLLKFSQNDSITYMTLHEPSLGSGEESWEASSAELERRCRL-------G 141

  Fly   193 EHVDQLSLISVPRNSS---PRVFPIATASLQRIGLGL-----------------------RGPFR 231
            ..|..||.|:.|..|.   ...|||      |..||:                       ..|:|
Zfish   142 SEVTSLSHITSPEKSENYFKLSFPI------RYCLGMTRLITIFVIVVLCSLFFSMYPDRESPWR 200

  Fly   232 LQENELAINASVPL----------PLLQVQVMRSYFDGEGMEIYIENAS----QVWQLDVVYPDL 282
            :    ||::::...          .||::||...:..  |||...|:..    ||.|.:...|
Zfish   201 M----LAVSSTESFSMNLTDFRDNSLLKLQVGGPFLG--GMEAVQESQEYILIQVEQTEEAGP-- 257

  Fly   283 IDATRDTKKQRTFEL--SPTDPLWLAQAN---RTELSFEFTSSIEGELPLQ----------LNVD 332
                   :::||.::  :.|.||...:::   ||. :||..||...::.:|          |::.
Zfish   258 -------RRRRTQQVLYNWTIPLHSQRSDQILRTR-TFEMVSSAPIQISVQAFLLDNQVVPLSMT 314

  Fly   333 ESPIY--KRDGVIYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWID 395
            ...:|  ....|:.|..:|.|:||:||:|||:||.||::.|..::..||.:..|||:.|::.|||
Zfish   315 NQSLYVTVETQVLIAGLILAGVYVLIIFEIVHRTLAAMLGSLSALAALAFIGDRPSLMTVVEWID 379

  Fly   396 VETLLLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLM 460
            .|||.|||||||||||.||||.|||.||.||:::.|.|||:|..|||..|:||:|||||||::|.
Zfish   380 YETLALLFGMMILVAIFSETGFFDYCAVKAYQLSRGRVWPMIIILCLIAAILSAFLDNVTTMMLF 444

  Fly   461 TPVTIRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISKNGVNFAVFTLHMLP 525
            ||||||||||:.|:|..:|:..||::|||||.|.|||||||||.||..:.|.|::||.||.:|..
Zfish   445 TPVTIRLCEVLNLDPRQVLIAEVIFTNIGGAATAVGDPPNVIIVSNQDLRKKGIDFAAFTGYMFL 509

  Fly   526 GVLLVMVQTYIQLRFKFRNISDLQFKDSPEVEELRHEIHVWKRAAASLSAYSKDEELVRQTLMKK 590
            |:.||::.::..||..|.| ..|..|:|.|:.||:|||.||::.|..::..|::|..|:..||:|
Zfish   510 GICLVLLTSFPFLRLLFWN-KKLYNKESSEIVELKHEILVWRQTAHRINPASREETAVKCLLMQK 573

  Fly   591 VNRLKRSLKKRMTA----VIEPAPNYQQTLANLQAKYPIRNKPLLIKCSAALVFVISLFFLHSVP 651
            |..|:..|:|::..    :.:...|::..:..||.|:.|.:|.||:||...|..||.:|||:|..
Zfish   574 VLNLESLLRKKLKTFQRQISQEDKNWEHNIQELQKKHRITDKVLLVKCLTVLGVVIFMFFLNSFV 638

  Fly   652 ELQRLSLGWTALLGAIFLIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMT 716
            ....|.|||.|:|||::|::||||:|.|.||.||||:|||||||||:|||||.:|.||::||..|
Zfish   639 PAIHLDLGWIAILGALWLLVLADIQDFEIILHRVEWATLLFFAALFVLMEALAQLQLIDYIGEQT 703

  Fly   717 EGIILGVGEDRRLMVAILIILWVSAVASAFVDNIPLTTMMVKITISLAQNSTLNLPLQPLVWALA 781
            ..:|..|.||.||.:||:::|||||:||:.:||||.|..|:.:.|:|:|::.:|||::||::|||
Zfish   704 AVLIKAVPEDERLAIAIILVLWVSALASSLIDNIPFTATMIPVLINLSQDADVNLPIKPLIFALA 768

  Fly   782 LGACLGGNGTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYLLVSHSLFAWH 846
            :|||||||||||||||||||||:||||||.|:|::||::|||:|:.:..:...|||.:|....|:
Zfish   769 MGACLGGNGTLIGASANVVCAGIAEQHGYGFSFMEFFRLGFPMMLMTCTIGMCYLLATHIGLHWN 833

  Fly   847  846
            Zfish   834  833

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hoe1	NP_608876.1	geminin-like_CC	68..>118	CDD:459243	7/30 (23%)
		P_permease	349..837	CDD:238536	261/491 (53%)
oca2	XP_021332872.2	None