Protein Alignment hoe1 and LOC1280249

DIOPT Version :10

• Sequence 1: NP_608876.1
• Gene: hoe1 / 249663
• FlyBaseID: FBgn0041150
• Length: 846
• Species: Drosophila melanogaster
• Sequence 2: XP_061512910.1
• Gene: LOC1280249 / 1280249
• VectorBaseID: AGAMI1_015065
• Length: 889
• Species: Anopheles gambiae
• Alignment Length: 837
• Identity: 416/837 - (49%)
• Similarity: 560/837 - (66%)
• Gaps: 71/837 - (8%)

  Fly    61 EVTEGALQVWRTLPERIRQDPSLASFRQ---EHERLHGD-----------VDQLHAEESELRVQN 111
            ||||.:|::|||||.:||.|||:.||:|   ||.|||||           :::...||.| ..::
Mosquito    73 EVTEASLELWRTLPPKIRHDPSMVSFQQVELEHARLHGDCHEDSFPEIQGLEEDDGEEDE-DDED 136

  Fly   112 GHHEETALANQPFTQIGINVTNEAGQ-----------------VRVLDGRDLENNNDDQHDEA-- 157
            ...|:....|:..|   ||||||.||                 |..|.|..:.|....:||:.
Mosquito   137 EEEEDEEYENEFIT---INVTNEEGQAKEIGHVKEKKEIPKPHVHHLAGHYIGNITPPKHDDIND 198

  Fly   158 -------EPHAKSLIRKYLIWFKIAILLVVWCVFTAFLMSNNEHVDQLSLISV-PRNSSPRVFPI 214
                   |.|.   .|||   .||..|.:.|.:..:|::..:|.:.:...:|: |..:...:.|.
Mosquito   199 TGQTNLDEDHP---FRKY---SKIICLFITWLLIMSFMVVKDEKMVEPKHLSISPGKTKAYILPH 257

  Fly   215 ATASLQRIGLGLRGPF------RLQENELAINASVPLPLLQVQVMRSYFDGEGMEIY----IENA 269
            ...| .||.:.|.|.|      .:.|:.|.:         .:|::.|..:|...:||    .:|.
Mosquito   258 LPQS-TRIKVTLEGTFLSEPYSNITEHYLEV---------YLQMLSSTLEGNSSDIYSSSSAKNI 312

  Fly   270 SQVWQLDVVYPDLIDATRDTKKQRTFELSPTDPLWLAQANRTELSFEFTSSIEGELPLQLNVDES 334
            |:.|.:.:|:|.|.|:....|:||.|::..::...|.|.|...:.....|:|:..:|:.:..|:|
Mosquito   313 SESWYIPIVHPYLFDSAPIVKEQRLFDIIDSNYEQLHQTNGGLVRLMIRSNIQASMPIAIRYDQS 377

  Fly   335 PIYKRDGVIYAAAVLCGLYVMIIWEIVNRTFAAIIASTLSVGILAALNSRPSMATIMGWIDVETL 399
            |:.:..||||||.||..|||:||||||:|||||:|||||::.||||||.||:|..|:|||||||:
Mosquito   378 PVNRDVGVIYAAFVLIFLYVLIIWEIVHRTFAAVIASTLAISILAALNDRPTMEDIIGWIDVETI 442

  Fly   400 LLLFGMMILVAILSETGVFDYLAVYAYKITNGHVWPLINCLCLFTAVLSSFLDNVTTVLLMTPVT 464
            ||||.||||||||:|||:||||:||.||||||.:|.||:||||.|.::|||||||||||||.|:|
Mosquito   443 LLLFSMMILVAILAETGIFDYLSVYIYKITNGKIWSLIHCLCLCTVLISSFLDNVTTVLLMAPIT 507

  Fly   465 IRLCEVMCLNPVPILMCMVIYSNIGGALTPVGDPPNVIIASNSYISKNGVNFAVFTLHMLPGVLL 529
            |||||||.:|||||||.:.:::||||..||||||||:||.||.||.|:||.|..||.|||.||::
Mosquito   508 IRLCEVMDMNPVPILMAITVHANIGGTTTPVGDPPNIIITSNQYILKHGVTFLTFTAHMLVGVII 572

  Fly   530 VMVQTYIQLRFKFRNISDLQFKDSPEVEELRHEIHVWKRAAASLSAYSKDEELVRQTLMKKVNRL 594
            |::.|.|.||..::||:.|:..:..|::|||..|.||:|||..:..||||..:||:||||||..|
Mosquito   573 VVITTNIHLRIIYKNINHLRMHEPKELKELRRNIKVWERAAGKIPPYSKDANIVRETLMKKVKLL 637

  Fly   595 KRSLKKRMTAVIEPAPNYQQTLANLQAKYPIRNKPLLIKCSAALVFVISLFFLHSVPELQRLSLG 659
            :...||:||....|...|:.||..||.::||:|:|||||.....||::|||||.|:|||:|||.|
Mosquito   638 RHQYKKKMTKGTVPEDIYRSTLEELQREHPIKNRPLLIKSGVVCVFIVSLFFLESIPELRRLSSG 702

  Fly   660 WTALLGAIFLIILADIEDMEAILARVEWSTLLFFAALFILMEALTELGLIEWIGNMTEGIILGVG 724
            |.||||.:.|:|::|..||:|:|:||||.|||||||:|.||||:..:|||:|||:.||.|||.|.
Mosquito   703 WAALLGVVLLLIISDKNDMDAVLSRVEWPTLLFFAAMFTLMEAVERMGLIDWIGHATETIILSVS 767

  Fly   725 EDRRLMVAILIILWVSAVASAFVDNIPLTTMMVKITISLAQNSTLNLPLQPLVWALALGACLGGN 789
            ||.||.|||:||||:||:.|||||:||:|.|||||.::|::.:.|.|||||:|||||.|.|||||
Mosquito   768 EDLRLAVAIVIILWISALTSAFVDSIPVTAMMVKIVVALSEKAYLGLPLQPMVWALAFGPCLGGN 832

  Fly   790 GTLIGASANVVCAGVAEQHGYKFTFLQFFKVGFPIMIGSIIVTTGYLLVSHSLFAWH 846
            |||:||||||:|||:||||||:|:|:.:||:|||||:.|::||||||:::|.:||||
Mosquito   833 GTLVGASANVICAGIAEQHGYRFSFMDYFKLGFPIMLVSVLVTTGYLIMAHVVFAWH 889

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
hoe1	NP_608876.1	geminin-like_CC	68..>118	CDD:459243	24/63 (38%)
		P_permease	349..837	CDD:238536	311/487 (64%)
LOC1280249	XP_061512910.1	None