Protein Alignment Hspa1l and Hsp70Bb

DIOPT Version :10

• Sequence 1: NP_997711.1
• Gene: Hspa1l / 24963
• RGDID: 1595925
• Length: 641
• Species: Rattus norvegicus
• Sequence 2: NP_524927.2
• Gene: Hsp70Bb / 48582
• FlyBaseID: FBgn0013278
• Length: 641
• Species: Drosophila melanogaster
• Alignment Length: 641
• Identity: 476/641 - (74%)
• Similarity: 553/641 - (86%)
• Gaps: 9/641 - (1%)

  Rat     8 AIGIDLGTTYSCVGVFQHGKVEIIANDQGNRTTPSYVAFTDTERLIGDAAKNQVAMNPQNTVFDA 72
            |||||||||||||||:|||||||||||||||||||||||||:||||||.|||||||||:||||||
  Fly     3 AIGIDLGTTYSCVGVYQHGKVEIIANDQGNRTTPSYVAFTDSERLIGDPAKNQVAMNPRNTVFDA 67

  Rat    73 KRLIGRKFNDPVVQSDMKLWPFQVINEAGKPKVLVSYKGEKKAFYPEEISSMVLTKMKETAEAFL 137
            |||||||::||.:..|||.|||:|:::.||||:.|.||||.|.|.||||||||||||||||||:|
  Fly    68 KRLIGRKYDDPKIAEDMKHWPFKVVSDGGKPKIGVEYKGESKRFAPEEISSMVLTKMKETAEAYL 132

  Rat   138 GHSVTNAVITVPAYFNDSQRQATKDAGVIAGLNVLRIINEPTAAAIAYGLDKGSHGERHVLIFDL 202
            |.|:|:|||||||||||||||||||||.|||||||||||||||||:||||||...|||:||||||
  Fly   133 GESITDAVITVPAYFNDSQRQATKDAGHIAGLNVLRIINEPTAAALAYGLDKNLKGERNVLIFDL 197

  Rat   203 GGGTFDVSILTIDDG-IFEVKATAGDTHLGGEDFDNRLVSHFVEEFKRKHKKDISQNKRAVRRLR 266
            |||||||||||||:| :|||::|||||||||||||||||:|..||||||:|||:..|.||:||||
  Fly   198 GGGTFDVSILTIDEGSLFEVRSTAGDTHLGGEDFDNRLVTHLAEEFKRKYKKDLRSNPRALRRLR 262

  Rat   267 TACERAKRTLSSSTQANLEIDSLYEGIDFYTSITRARFEELCADLFRGTLEPVEKSLRDAKMDKA 331
            ||.|||||||||||:|.:|||:|:||.||||.::|||||||||||||.||:||||:|.||||||.
  Fly   263 TAAERAKRTLSSSTEATIEIDALFEGQDFYTKVSRARFEELCADLFRNTLQPVEKALNDAKMDKG 327

  Rat   332 KIHDIVLVGGSTRIPKVQKLLQDYFNGRDLNKSINPDEAVAYGAAVQAAILMGDKSEKVQDLLLL 396
            :|||||||||||||||||.|||::|:|::||.|||||||||||||||||||.||:|.|:||:||:
  Fly   328 QIHDIVLVGGSTRIPKVQSLLQEFFHGKNLNLSINPDEAVAYGAAVQAAILSGDQSGKIQDVLLV 392

  Rat   397 DVAPLSLGLETAGGVMTVLIKRNSTIPTKQTQIFTTYSDNQPGVLIQVYEGERAMTRDNNLLGRF 461
            ||||||||:||||||||.||:||..||.|||:.|:|||||||||.|||||||||||:|||.||.|
  Fly   393 DVAPLSLGIETAGGVMTKLIERNCRIPCKQTKTFSTYSDNQPGVSIQVYEGERAMTKDNNALGTF 457

  Rat   462 DLTGIPPAPRGVPQIEVTFDIDANGILNVTAMDKSTGKANKITITNDKGRLSKEEIERMVQEAER 526
            ||:|||||||||||||||||:||||||||:|.:.|||||..|||.|||||||:.||:|||.|||:
  Fly   458 DLSGIPPAPRGVPQIEVTFDLDANGILNVSAKEMSTGKAKNITIKNDKGRLSQAEIDRMVNEAEK 522

  Rat   527 YKAEDEGQREKIAAKNALESYAFNMKSAVGDEGLKDKISESDKKKILDKCSEVLSWLEANQLAEK 591
            |..|||..|::|.::||||||.||:|.:| ::....|:.|:||..:||||:|.:.||::|..|||
  Fly   523 YADEDEKHRQRITSRNALESYVFNVKQSV-EQAPAGKLDEADKNSVLDKCNETIRWLDSNTTAEK 586

  Rat   592 EEFDHKRKELENMCNPIITKLYQSGCTGPTCAPGYTPGRAA------TGPTIEEVD 641
            ||||||.:||...|:||:||::|.| .|....||...|:.|      :|||:||||
  Fly   587 EEFDHKMEELTRHCSPIMTKMHQQG-AGAAGGPGANCGQQAGGFGGYSGPTVEEVD 641

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hspa1l	NP_997711.1	PTZ00009	3..641	CDD:240227	474/639 (74%)
		Nucleotide-binding domain (NBD). /evidence=ECO:0000250|UniProtKB:P11142	3..388		309/380 (81%)
		Substrate-binding domain (SBD). /evidence=ECO:0000250|UniProtKB:P11142	396..511		91/114 (80%)
Hsp70Bb	NP_524927.2	PTZ00009	2..641	CDD:240227	474/639 (74%)