Protein Alignment FTH1 and Fer3HCH

DIOPT Version :9

• Sequence 1: NP_002023.2
• Gene: FTH1 / 2495
• HGNCID: 3976
• Length: 183
• Species: Homo sapiens
• Sequence 2: NP_572854.1
• Gene: Fer3HCH / 32260
• FlyBaseID: FBgn0030449
• Length: 186
• Species: Drosophila melanogaster
• Alignment Length: 167
• Identity: 76/167 - (45%)
• Similarity: 112/167 - (67%)
• Gaps: 6/167 - (3%)

Human     9 VRQNYHQDSEAAINRQINLELYASYVYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKL 73
            ||||:.:..|..:|.|||:||.||:.||:|:|:|||.|::.....::||..|.||||||||:|..
  Fly    16 VRQNFAKSCEKKLNDQINMELKASHQYLAMAYHFDRSDISSPGMHRFFLKASVEEREHAEKIMTY 80

Human    74 QNQRGGRIFLQDIKKP-DCDDWESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETH 137
            .|:|||.|.|..:.:| .|  :.|.|:|::.|:.:|..||:.||:||.||..:.||:||||||.:
  Fly    81 MNKRGGLIILSSVPQPLPC--FASTLDALKHAMKMELEVNKHLLDLHALAGKEADPNLCDFIEAN 143

Human   138 YLNEQVKAIKELGDHVTNLRKMGAPESGLAEYLFDKH 174
            :|.|||...|.|.|:::.|.|   .::.:.|:||||:
  Fly   144 FLQEQVDGQKILADYISQLEK---AQNQVGEFLFDKY 177

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FTH1	NP_002023.2	Euk_Ferritin	14..174	CDD:153114	71/160 (44%)
Fer3HCH	NP_572854.1	Euk_Ferritin	24..177	CDD:153114	71/157 (45%)
		Ferritin	25..165	CDD:278632	67/144 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	128	1.000	Domainoid score	I5305
eggNOG	1	0.900	-	-		E1_COG1528
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	144	1.000	Inparanoid score	I4447
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1249457at2759
OrthoFinder	1	1.000	-	-		FOG0000169
OrthoInspector	1	1.000	-	-		otm41906
orthoMCL	1	0.900	-	-		OOG6_100688
Panther	1	1.100	-	-	LDO	PTHR11431
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4342
SonicParanoid	1	1.000	-	-		X152
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	12	11.900