DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32236 and Cwc27

DIOPT Version :9

Sequence 1:	NP_729026.1	Gene:	CG32236 / 249170	FlyBaseID:	FBgn0046793	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001347023.1	Gene:	Cwc27 / 67285	MGIID:	1914535	Length:	472	Species:	Mus musculus

Alignment Length:	186	Identity:	54/186 - (29%)
Similarity:	72/186 - (38%)	Gaps:	54/186 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    86 RRLK-----SIKSAGD----------SLGFHARLLNRSQLAGEFNQKQEIFRKNMELLGRINKTN 135
            :|||     |:|||||          .|...||.|.|..||.:  ||:|...|..|  ||..:..
Mouse   291 KRLKKDASASVKSAGDGEKKPASRSEELRKEARQLKRELLAAK--QKKETAIKVEE--GREEEEA 351

  Fly   136 RLKGGVDSFNRH---FPALQSNRNKIRELADRLSQENRQLGCRLSQVKSK--------------- 182
            ...|.|..:.|.   :.||:..:.|     ...|:|::.|.. |||.|||
Mouse   352 APDGAVAEYRREKQKYEALRKQQPK-----KGTSREDQTLAL-LSQFKSKLTQAITETPENSVPE 410

  Fly   183 --VDSHNPWVPPVKPLEQK------ASDETVSTFLPYMPSPRLGKR---SAQILLR 227
              |:....|:..|...|.|      ||.:...||..|.|...:.||   .::.|||
Mouse   411 AEVEDDEGWMSHVLQFEDKTRKVKDASMQDSDTFEIYDPRNPVNKRRREESKKLLR 466

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32236	NP_729026.1	KIAA1430	85..177	CDD:290590	32/108 (30%)
CG32236	NP_729026.1	cyclophilin	227..385	CDD:294131	1/1 (100%)
Cwc27	NP_001347023.1	cyclophilin_CeCYP16-like	8..178	CDD:238906
Cwc27	NP_001347023.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	431..472		11/36 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900