DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG32236 and ppifb

DIOPT Version :9

Sequence 1:	NP_729026.1	Gene:	CG32236 / 249170	FlyBaseID:	FBgn0046793	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001032199.2	Gene:	ppifb / 641328	ZFINID:	ZDB-GENE-051030-126	Length:	192	Species:	Danio rerio

Alignment Length:	200	Identity:	44/200 - (22%)
Similarity:	75/200 - (37%)	Gaps:	57/200 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   216 RLGKRSAQILLRPIIYFDMAVRENNQFMGRLLLQLYTELSPEVVLEFVRMATHNDVGCHR----- 275
            ||.....|....|:::||:|.  :||.:||:..:|..::.|:....|..:.|    |.|.
Zfish    19 RLYSTGVQANNNPVVFFDIAA--DNQPLGRVTFELNADVVPKTAENFRALCT----GEHGFGYKG 77

  Fly   276 --FVRIFSNLWMEAELVPAVHDSLHNHHSVKYSFLDPSKITGVLSYPWDYRRHFPQ--------- 329
              |.|:......:.       ....||:.           ||..|.   |...||.
Zfish    78 SIFHRVIPQFMCQG-------GDFTNHNG-----------TGGKSI---YGPRFPDENFKLKHTG 121

  Fly   330 -GLLS-------------YTISFKQSVIPWQRVIFGRVCGGLRVLQNCHEFGTKNGKTKKTVIVT 380
             |:||             :..:.|...:..:.|:||.|..|:.|::.....|:::|:|.:.:.:|
Zfish   122 PGILSMANAGVNTNGSQFFICTAKTEWLDGRHVVFGSVKEGMDVVRKVEALGSRSGRTAQRISIT 186

  Fly   381 RCGLL 385
            .||.|
Zfish   187 DCGEL 191

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32236	NP_729026.1	KIAA1430	85..177	CDD:290590
CG32236	NP_729026.1	cyclophilin	227..385	CDD:294131	40/187 (21%)
ppifb	NP_001032199.2	cyclophilin_ABH_like	31..189	CDD:238907	38/184 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810