DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG32236 and PPIL1

DIOPT Version :9

Sequence 1:NP_729026.1 Gene:CG32236 / 249170 FlyBaseID:FBgn0046793 Length:385 Species:Drosophila melanogaster
Sequence 2:NP_057143.1 Gene:PPIL1 / 51645 HGNCID:9260 Length:166 Species:Homo sapiens


Alignment Length:163 Identity:33/163 - (20%)
Similarity:56/163 - (34%) Gaps:71/163 - (43%)


- Green bases have known domain annotations that are detailed below.


  Fly   228 PIIYFDMAVRENNQFMGRLLLQLYTELSPEVVLEFVRMAT---HNDVGCHRFVRIF--------- 280
            |.:|.:.:       ||.::|:||.:.:|:....|..:|.   :|....||.::.|         
Human    12 PNVYLETS-------MGIIVLELYWKHAPKTCKNFAELARRGYYNGTKFHRIIKDFMIQGGDPTG 69

  Fly   281 -----SNLW---MEAELVPAVHDSLHNHHSVKYSFLDPSKITGVLSYPWDYRRHFPQGLLSYT-- 335
                 ::::   .|.||.|.:                  |.||.             |:|:..  
Human    70 TGRGGASIYGKQFEDELHPDL------------------KFTGA-------------GILAMANA 103

  Fly   336 ------ISFKQSVIPWQ-----RVIFGRVCGGL 357
                  ..|..::.|.|     ..||||||.|:
Human   104 GPDTNGSQFFVTLAPTQWLDGKHTIFGRVCQGI 136

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG32236NP_729026.1 KIAA1430 85..177 CDD:290590
cyclophilin 227..385 CDD:294131 33/163 (20%)
PPIL1NP_057143.1 cyclophilin_SpCYP2_like 15..161 CDD:238903 32/160 (20%)
Cyclosporin A binding. /evidence=ECO:0000305|PubMed:16595688 54..65 3/10 (30%)