DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG32236 and Ppil2

DIOPT Version :9

Sequence 1:	NP_729026.1	Gene:	CG32236 / 249170	FlyBaseID:	FBgn0046793	Length:	385	Species:	Drosophila melanogaster
Sequence 2:	NP_001017383.1	Gene:	Ppil2 / 360746	RGDID:	1309484	Length:	521	Species:	Rattus norvegicus

Alignment Length:	363	Identity:	77/363 - (21%)
Similarity:	134/363 - (36%)	Gaps:	117/363 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 DHRRLKSIKSAG--------DSLGFHARLLNRSQLAGEFNQKQEIFRKNMELLGRINKTNRLKGG 140
            |:..:.:|::.|        :.|...|:.| |..|..|...:|:|....       :.||..|..
  Rat   112 DNTHIVAIRTTGNVYTYEAVEQLNIKAKNL-RDLLTDEPFSRQDIITLQ-------DPTNLDKFN 168

  Fly   141 VDSFNRHFPALQSNRNKIRELADRLSQE--------NRQLGCRLSQVKSKVDSHNPWVPPVKPLE 197
            |.||..    :::|...|....::..|:        |.:....|.::..:..........:||.|
  Rat   169 VSSFFH----VKNNMRMIDPDEEKAKQDPSYYLKNTNAETRETLQELYKEFKGDEILAATMKPPE 229

  Fly   198 QKASDET----VSTFLPYMPSPRLGKRSAQI---LLRPIIYFDMAVRENN----QFM-------- 243
            :|..|:.    .||          ||.||..   .:.|....:.||.:.:    ||:
  Rat   230 KKKVDQLNAAHYST----------GKVSASFTSTAMVPETTHEAAVIDEDVLRYQFVKKKGYVRL 284

  Fly   244 ----GRLLLQLYTELSPEVVLEFVRMATHNDVGCHRFVRIFSNLWMEAELVPAVHDSLHNHHSVK 304
                |.|.|:|:.:|:|:.              |..|:::....:         :|....|.|::
  Rat   285 HTNKGDLNLELHCDLTPKT--------------CENFIKLCKKQY---------YDGTIFHRSIR 326

  Fly   305 YSFL----DPSKI-TGVLSYPW------DYR---RHFPQGLLS------------YTISFKQ-SV 342
             :|:    ||:.. ||..|| |      ::|   .|..:|:||            :.|:|:. :.
  Rat   327 -NFVIQGGDPTGTGTGGESY-WGKPFKDEFRPNLSHTGRGVLSMANSGPNTNKSQFFITFRSCAY 389

  Fly   343 IPWQRVIFGRVCGG---LRVLQNCHEFGTKNGKTKKTV 377
            :..:..|||||.||   |..::|. |...|..:.|:.|
  Rat   390 LDKKHTIFGRVVGGFDTLTAMENV-ESDPKTDRPKEEV 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG32236	NP_729026.1	KIAA1430	85..177	CDD:290590	20/107 (19%)
CG32236	NP_729026.1	cyclophilin	227..385	CDD:294131	44/197 (22%)
Ppil2	NP_001017383.1	Ubox	42..96	CDD:128780
Ppil2	NP_001017383.1	cyclophilin_RING	281..440	CDD:238904	39/172 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0652
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900