Protein Alignment ALPL and phu

DIOPT Version :10

• Sequence 1: NP_000469.3
• Gene: ALPL / 249
• HGNCID: 438
• Length: 524
• Species: Homo sapiens
• Sequence 2: NP_649897.4
• Gene: phu / 41135
• FlyBaseID: FBgn0043791
• Length: 546
• Species: Drosophila melanogaster
• Alignment Length: 252
• Identity: 60/252 - (23%)
• Similarity: 85/252 - (33%)
• Gaps: 76/252 - (30%)

Human   305 PPVLSLHSSSE-----TPYLLKETSKGGGQGEDRNLLYYSKLGLVVPSGGPASANQSIDRSG-PL 363
            ||.:::..|.|     |....|..|.|      .|:     |||||.|.........|...| |:
  Fly   171 PPEIAMTMSPEQRAQFTEVPEKIVSDG------MNI-----LGLVVFSVALGIVIGVIGEDGKPM 224

Human   364 ---VKSLLRRSLSMDSQVPVYSPSIDLKSSQGSSTAANEAPGSVFCSMSQKSSLKDCSEKKALDD 425
               .|||...|:.:...|.:|||                 .|..|...:|...:||..:
  Fly   225 KNFFKSLEACSMKLIGWVIIYSP-----------------VGITFLIAAQIVGMKDPGQ------ 266

Human   426 RPQVLQPHRLRSFSASQSTDREEASPVTEVRIKTEPSSPL-------SDPSDIIRVTVGGDAAAA 483
                 :.|||..:         ..:.:..:.|......||       .:|...    |||.|.|.
  Fly   267 -----ELHRLMGY---------VITVILGLLIHAFVVIPLLCVVLARRNPIKF----VGGMAQAL 313

Human   484 AVA-AAAAAAATRDLPLKTEEDQRDMSRLPAKRRFQTDRRSPLKKAKANEHGPAVSE 539
            ..| |.::::||..|.:|..|:...:.  |...||..    || .|..|..|.|:.|
  Fly   314 LTALATSSSSATLPLSIKCCEENNKVD--PRVTRFVL----PL-GATINMDGTALYE 363

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ALPL	NP_000469.3	Alk_phosphatase	51..490	CDD:395188	45/201 (22%)
phu	NP_649897.4	alkPPc	93..530	CDD:214515	60/252 (24%)