Protein Alignment Tbxas1 and Cyp6t3

DIOPT Version :10

• Sequence 1: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Sequence 2: NP_610745.1
• Gene: Cyp6t3 / 36318
• FlyBaseID: FBgn0033697
• Length: 501
• Species: Drosophila melanogaster
• Alignment Length: 547
• Identity: 146/547 - (26%)
• Similarity: 240/547 - (43%)
• Gaps: 84/547 - (15%)

  Rat    15 VVTVTLSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPF-----VGNLMFFRQGFWESHLEL---- 70
            ::.:.|.::.:..|.::....:...|..||.|..||.:     :|.|:|.|..|.:...:|
  Fly     1 MLLIWLLLLTIVTLNFWLRHKYDYFRSRGIPHLPPSSWSPMGNLGQLLFLRISFGDLFRQLYADP 65

  Rat    71 RERYGPLCGYYLGRRMYIVISDPDMIKEVLVENFSNFSNRM--ASGLEPKLIADSVLMLRDRRWE 133
            |.....:.|:::.:...:::.||::|::||::||:||.||.  |...:| :.|.::.:.:...|:
  Fly    66 RNGQAKIVGFFIFQTPALMVRDPELIRQVLIKNFNNFLNRFESADAGDP-MGALTLPLAKYHHWK 129

  Rat   134 EVRGALMSAFSPEKLNEMTPLISQACEL---LLSHLKHSAASGDAFD----IQRCYCCFTTNVVA 191
            |.|..:...|:..::.::  :.||..::   |..:|....  ||..:    :.|....:||:|..
  Fly   130 ESRQCMSQLFTSGRMRDV--MYSQMLDVASDLEQYLNRKL--GDRLERVLPLGRMCQLYTTDVTG 190

  Rat   192 SVAFGIEVNSQDAPEDPFVQHCQRVFAFSTPRPLLALILSFPSIMVPLARILPNKNRDELNG--- 253
            ::.:.:.|..........:...:.:|. :.||.    :|.|.|:.     .||     :..|
  Fly   191 NLFYSLNVGGLRRGRSELITKTKELFN-TNPRK----VLDFMSVF-----FLP-----KWTGVLK 240

  Rat   254 ---FFNTLIRNVIALRDKQTAEERRGDFLQMVLDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQ 315
               |.....|.:..|.|.. .|..:||.:..:...|.|.||.....
  Fly   241 PKVFTEDYARYMRHLVDDH-HEPTKGDLINQLQHFQLSRSSNHYSQ------------------- 285

  Rat   316 RCHPTSTAKPLTVDEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPA 380
              ||         |.:|.||.:.|:||.|.::..:.|..|.||..|:.||||..|:.........
  Fly   286 --HP---------DFVASQAGIILLAGFETSSALMGFTLYELAKAPDIQERLRSELREAFISTAT 339

  Rat   381 PEYCNLQEGLPYLDMVVAETLRMYPPAFRFTRE---AAQDCEVLGQH----IPAGSVLEIAVGAL 438
            ..|..|.. ||||.||..|.||:||.|....||   :|.:...|..|    :|.|....|::..|
  Fly   340 LSYDTLMT-LPYLKMVCLEALRLYPAAAFVNRECTSSASEGFSLQPHVDFIVPPGMPAYISILGL 403

  Rat   439 HHDPEHWPNPETFDPERFTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFE 503
            |.|...||.|..||||||..|......|.||:||||||..|:|.|||:|.:||.::.:|.::..|
  Fly   404 HRDERFWPEPCVFDPERFGPERSRHIHPMTYIPFGAGPHGCIGSRLGVLQLKLGIVHILKQYWVE 468

  Rat   504 ACPETQVPLQLESKS-ALCPKNGVYVK 529
            .|..|...::...|| .|..:|.:|::
  Fly   469 TCERTVSEIRFNPKSFMLESENEIYLR 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	130/475 (27%)
Cyp6t3	NP_610745.1	CYP6-like	68..493	CDD:410679	130/476 (27%)