Protein Alignment Wnt3 and Wnt5

DIOPT Version :10

• Sequence 1: XP_017452517.1
• Gene: Wnt3 / 24882
• RGDID: 3972
• Length: 367
• Species: Rattus norvegicus
• Sequence 2: NP_476924.1
• Gene: Wnt5 / 32838
• FlyBaseID: FBgn0010194
• Length: 1004
• Species: Drosophila melanogaster
• Alignment Length: 507
• Identity: 124/507 - (24%)
• Similarity: 171/507 - (33%)
• Gaps: 223/507 - (43%)

  Rat    63 GQGVANLALQGAFRSHHR------PLYLSIVALN----------------------SVCPSTKRI 99
            |.|.||        |||.      ..|...:.||                      ||.|:..|
  Fly   519 GAGSAN--------SHHNDTTPTADAYSETIDLNPNNCYSAIGLSNSQKKQCVKHTSVMPAISR- 574

  Rat   100 ILRSGLLRA-----------------TGGSLALHPMT--ATRESAFVHAIASAGVAFAVTRSCAE 145
                |...|                 |.......|||  |..|.||:||:|:|.|...:.|:|.:
  Fly   575 ----GARAAIQECQFQFKNRRWNCSTTNDETVFGPMTSLAAPEMAFIHALAAATVTSFIARACRD 635

  Rat   146 GTSTICGCDSHHKGPP--GEGWKWGGCSEDADFGVLVSREFADARENRPD--------------- 193
            |....|.| |....|.  .:.||||||.::.:|....:.:|.|:||...:
  Fly   636 GQLASCSC-SRGSRPKQLHDDWKWGGCGDNLEFAYKFATDFIDSREKETNRETRGVKRKREEINK 699

  Rat   194 ----------------------------------------------------------------- 193
                                                                             
  Fly   700 NRMHSDDTNAFNIGIKRNKNVDAKNDTSLVVRNVRKSTEAENSHILNENFDQHLLELEQRITKEI 764

  Rat   194 ----------------------------------------------------------------- 193
                                                                             
  Fly   765 LTSKIDEEEMIKLQEKIKQEIVNTKFFKGEQQPRKKKRKNQRAAADAPAYPRNGIKESYKDGGIL 829

  Rat   194 --------ARSAMNKHNNEAGRTTILDHMHLKCKCHGLSGSCEVKTCWWAQPDFRAIGDFLKDKY 250
                    |||.||.|||||||..::....:.|||||:||||.:.|||......|.|||:|::||
  Fly   830 PRSTATVKARSLMNLHNNEAGRRAVIKKARITCKCHGVSGSCSLITCWQQLSSIREIGDYLREKY 894

  Rat   251 DSASEMVVEKHRESRGWVETLRAKYALFKPPTERDLVYYENSPNFCEPNPETGSFGTRDRTCNVT 315
            :.|:::.:.|    ||   .|:.|...||.||..||:|.:.||::|..:......||..|.|:..
  Fly   895 EGATKVKINK----RG---RLQIKDLQFKVPTAHDLIYLDESPDWCRNSYALHWPGTHGRVCHKN 952

  Rat   316 SHGIDGCDLLCCGRGHNTRTEKRKEKCHCVFHWCCYVSCQECIRIYDVHTCK 367
            |.|::.|.:||||||:||:.....|:|:|.|||||.|.|:.|.::.:.||||
  Fly   953 SSGLESCAILCCGRGYNTKNIIVNERCNCKFHWCCQVKCEVCTKVLEEHTCK 1004

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Wnt3	XP_017452517.1	Wnt_Wnt3_Wnt3a	<119..367	CDD:381709	103/404 (25%)
Wnt5	NP_476924.1	Wnt_Wnt5	548..1004	CDD:381711	112/468 (24%)