Protein Alignment FRZB and frzb

DIOPT Version :9

• Sequence 1: NP_001454.2
• Gene: FRZB / 2487
• HGNCID: 3959
• Length: 325
• Species: Homo sapiens
• Sequence 2: NP_001005438.1
• Gene: frzb / 448021
• XenbaseID: XB-GENE-481353
• Length: 319
• Species: Xenopus tropicalis
• Alignment Length: 315
• Identity: 236/315 - (74%)
• Similarity: 264/315 - (83%)
• Gaps: 12/315 - (3%)

Human    16 LLALAALCLLRVPGARAAACEPVRIPLCKSLPWNMTKMPNHLHHSTQANAILAIEQFEGLLGTHC 80
            |:.:..|.||.:|.|..|:|||||||:|||:||||||||||||||||||||||||||||||.|.|
 Frog    12 LMVIPGLVLLSLPNAHCASCEPVRIPMCKSMPWNMTKMPNHLHHSTQANAILAIEQFEGLLTTEC 76

Human    81 SPDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRG 145
            |.||||||||||||||||||||||||||||||||||.|||||||||||:|||:||||||||||||
 Frog    77 SQDLLFFLCAMYAPICTIDFQHEPIKPCKSVCERARAGCEPILIKYRHTWPESLACEELPVYDRG 141

Human   146 VCISPEAIVTADGA-----DFPMDSSNGNCRGASSERCKCKPIRATQKTYFRNNYNYVIRAKVKE 205
            ||||||||:|.:..     ||||||:||||...:.|.|||||::|:||||.:|||||||||||||
 Frog   142 VCISPEAIITVEQGTDSMPDFPMDSNNGNCGSTAGEHCKCKPMKASQKTYLKNNYNYVIRAKVKE 206

Human   206 IKTKCHDVTAVVEVKEILKSSLVNIPRDTVNLYTSSGCLCPPLNVNEEYIIMGYEDEERSRLLLV 270
            :|.||||.||:|||||||||||||||:|||.|||:||||||.|..|||||||||||:||:|||||
 Frog   207 VKVKCHDATAIVEVKEILKSSLVNIPKDTVTLYTNSGCLCPQLVANEEYIIMGYEDKERTRLLLV 271

Human   271 EGSIAEKWKDRLGKKVKRWDMKLRHLGLSKSDSSNSDSTQSQKSGRNSNPRQARN 325
            |||:||||:|||.|||||||.|||....||       ...:|.:.:|||.||||:
 Frog   272 EGSLAEKWRDRLAKKVKRWDQKLRRPRKSK-------DPVAQNTNKNSNSRQARS 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRZB	NP_001454.2	CRD_SFRP3	32..157	CDD:143550	113/124 (91%)
		NTR_Sfrp3_like	188..297	CDD:239636	89/108 (82%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	297..325		9/27 (33%)
frzb	NP_001005438.1	CRD_SFRP3	28..153	CDD:143550	113/124 (91%)
		NTR_Sfrp3_like	189..299	CDD:239636	89/109 (82%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	222	1.000	Domainoid score	I13646
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1126
Inparanoid	1	1.050	497	1.000	Inparanoid score	I7736
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG50423
OrthoDB	1	1.010	-	-		D1339129at2759
OrthoFinder	1	1.000	-	-		FOG0010299
OrthoInspector	1	1.000	-	-		oto158618
Panther	1	1.100	-	-	LDO	PTHR11309
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X7712
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	12	12.080