Protein Alignment Ugt1a1 and Ugt36A1

DIOPT Version :9

• Sequence 1: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Sequence 2: NP_001285591.1
• Gene: Ugt36A1 / 44058
• FlyBaseID: FBgn0015663
• Length: 537
• Species: Drosophila melanogaster
• Alignment Length: 579
• Identity: 155/579 - (26%)
• Similarity: 267/579 - (46%)
• Gaps: 99/579 - (17%)

  Rat     1 MSVVCRSSCSLLLLPCLLLCVLG-PSASHAGKLL-VIPIDG-SHWLSMLGVIQQLQQKGHEVVVI 62
            |:...||.    :|..:||.:|| |....||.:| |.|..| ||:..::.::.:|..:||::.||
  Fly     1 MTTCLRSG----VLIIVLLGILGIPEPISAGNILAVYPHFGFSHFKVVMPILNELAHRGHDITVI 61

  Rat    63 A----PEASIHIKEGSFYTMRKYPVPFQNENVTAAFVELGRSVFDQDPFLLRVVKTYNKVKRDSS 123
            :    |:|      |::....:..:....|:.::..:.|             |..|.:...|...
  Fly    62 SYVKNPQA------GAYPNYEELLISAPGEDQSSTTINL-------------VPLTEHTPTRSLG 107

  Rat   124 MLL-----------SGCSHLLHNAEFMASLEQSH---FDALLTDPF-LPCGSIVAQYLSLPAV-- 171
            :|:           ..|.||..:.....::|:..   :|.|||:.| ..|...:|:.|:||.:
  Fly   108 VLIREYVDLHEEGQKTCEHLFASGHIERAIERHRNKPYDLLLTEYFNSDCQLALAKLLNLPIIGL 172

  Rat   172 -------YFLNALPCSLDLEATQCPAPLSYVPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVY 229
                   |:.:    .:||..|  ||   ::.........::|:.:|:.|.:.|....||    |
  Fly   173 STCALMPYYYD----RIDLPDT--PA---FIQSEFVGFAGQLNWHERLLNFVQAKLLKFL----Y 224

  Rat   230 SPYGSLA-TEILQK----EVTVKDLLSPASIWLMRNDFVKDY----PRPIMPNMVFIGGINCLQK 285
            ..:.:.| .|:::|    ||.|:::....:.::..|   :.|    .||.....|.|||:: :.|
  Fly   225 KYHSNRADNELVRKYLGVEVDVEEVARTQTAFIFGN---QHYSLMGSRPQSLQFVEIGGVH-ITK 285

  Rat   286 KA---LSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTR-P 344
            ||   |.|....::|.|.| |::..|.||||  |.|.|.|...|.|.|...|..::|::.... |
  Fly   286 KAEQELPQNIANFLNQSAE-GVIFISWGSMVRASSIDEDKLSAILEVLKSQPLKIIWKWEADETP 349

  Rat   345 SNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMETR 409
            ...|...:.|||.||..||.|||.:.|.:|.|..|..|.:..|.|:::.|::|||..||..::.|
  Fly   350 DTDASKFLFVKWAPQLALLCHPKVKLFWSHGGLLGTTESVHCGKPLLVTPIYGDQFLNAFSVQNR 414

  Rat   410 GAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHK--G 472
            |.|:.|:..::|..:|:.||..:..| ||.:..:.:|.:..:|...||:.|::.||:|:.:.  .
  Fly   415 GMGLKLDYQDITVPNLKKALAELSKN-SYAQRSLEVSKVFNERQQTPLESAIWSVEHVISNGLIA 478

  Rat   473 APHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVYKSCAYGCRKCFGGKGRVKKSHK 531
            |..|:....:|..:.|||||.:..:|   |.::.::...| |.|:     :...|.:||
  Fly   479 ARLLQSPGIELNGFVYHSLDSVALIL---LPLILLILVLC-YLCK-----RNPSKLAHK 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	142/542 (26%)
		egt	<263..509	CDD:223071	84/257 (33%)
Ugt36A1	NP_001285591.1	egt	8..475	CDD:223071	136/508 (27%)
		UDPGT	38..501	CDD:278624	132/500 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910