Protein Alignment FRG1 and frg1

DIOPT Version :10

• Sequence 1: NP_004468.1
• Gene: FRG1 / 2483
• HGNCID: 3954
• Length: 258
• Species: Homo sapiens
• Sequence 2: NP_595824.1
• Gene: frg1 / 2541328
• PomBaseID: SPBP23A10.12
• Length: 245
• Species: Schizosaccharomyces pombe
• Alignment Length: 273
• Identity: 72/273 - (26%)
• Similarity: 116/273 - (42%)
• Gaps: 55/273 - (20%)

Human     9 STKLVLKGTKTKSKKKKSKDKKRKREEDEETQLDIVGIWWTVTN-FGEISGTIAI-EMDKGTYIH 71
            |.:|..||.| |.:|||.|:.|..:...|..:.|   .:||..| ..|:.|...| ::|
pombe     2 SMRLTFKGDK-KIQKKKKKNTKSLQSSLESAEND---PFWTDANELNELEGPAVIYKID------ 56

Human    72 ALDNGLFTLG----------APHKEVDEGPSPPEQFTAVKLSDSRIALKSGYGKYLGINSDGLVV 126
              |:...:||          .|..:|...|....|...:.:.::.|.|||..|||:..:..|.:.
pombe    57 --DDAGVSLGIEEVKESCVLLPLDKVSLEPELTRQVFLLSILNNTILLKSCLGKYMSCSKSGDLY 119

Human   127 GRSDAIGPREQWEPVFQNGKMALLASNSCFIRCNEAGDIEAKSKTAGEEEMIKIRSCAERETKKK 191
            ...:|:|.:|||  :.:|......|..|...:         |..|...|:..:..:|.      .
pombe   120 CTQEAVGSQEQW--IAENLGSGFWAWKSVSTK---------KYLTLSREKQDQAIACV------S 167

Human   192 DDIPEEDKGNVKQCEINYVKKFQS--FQDHKL-----------KISKEDSKILKKARKDGFLHET 243
            |.:..|.|..:: .:..::||.:|  |.:..:           |:|.::.|.||||.|:|.|||.
pombe   168 DTVIPEAKWRIR-VQTRFLKKNKSSLFDNPTIHSRQLESMAGRKLSTDEKKTLKKAFKEGVLHEA 231

Human   244 LLDRRAKLKADRY 256
            |||.|...::|:|
pombe   232 LLDLRVSSRSDKY 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FRG1	NP_004468.1	Nuclear localization signal. /evidence=ECO:0000255	22..32		5/9 (56%)
		FRG1	67..256	CDD:368803	51/211 (24%)
		Bipartite nuclear localization signal. /evidence=ECO:0000255	235..251		9/15 (60%)
frg1	NP_595824.1	beta-trefoil_FSCN_fungal_FRG1-like	31..181	CDD:467447	38/178 (21%)