Protein Alignment Gclm and GCY1

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_014763.1
• Gene: GCY1 / 854287
• SGDID: S000005646
• Length: 312
• Species: Saccharomyces cerevisiae
• Alignment Length: 299
• Identity: 69/299 - (23%)
• Similarity: 118/299 - (39%)
• Gaps: 85/299 - (28%)

  Fly    14 ISTG-NIIATELG--QRKSNE-------ELYDGLKITLHTDSTAERVVVEKEIDELHGRVQRATQ 68
            ::|| .|....||  |.|.|:       .|.||.:   |.|:.|               :.|...
Yeast    14 LNTGAQIPQIGLGTWQSKENDAYKAVLTALKDGYR---HIDTAA---------------IYRNED 60

  Fly    69 ELTTRLTENG--RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVL--------AYHP 123
            ::...:.::|  |.||.:..|::..:|....|  |:::.|..|.:.:||..::        ||..
Yeast    61 QVGQAIKDSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARLDPAYIK 123

  Fly   124 NAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADLD 188
            |....:.|   ||   .:.|.....|||:.....|.:.||.:..||          ..:|:::..
Yeast   124 NEDILSVP---TK---KDGSRAVDITNWNFIKTWELMQELPKTGKT----------KAVGVSNFS 172

  Fly   189 AAALEELHNSA--QVVPTIAQVNLSTCCVVP-PELQEFCTAHDIQLNTHS-----DPELL----- 240
            ...|::|..|.  ::.|...||.:..  ::| .||..||.:..|.:..:|     |..||
Yeast   173 INNLKDLLASQGNKLTPAANQVEIHP--LLPQDELINFCKSKGIVVEAYSPLGSTDAPLLKEPVI 235

  Fly   241 LPVEQFDGLVPGY-TIDWTLRYQVHVRCRGVLTAKGYIV 278
            |.:.:.:.:.||: .|.|      ||:       :||:|
Yeast   236 LEIAKKNNVQPGHVVISW------HVQ-------RGYVV 261

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	39/166 (23%)
GCY1	NP_014763.1	AKR_AKR3A1-2	7..296	CDD:381343	69/299 (23%)