Protein Alignment Gclm and ARA1

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_009707.3
• Gene: ARA1 / 852446
• SGDID: S000000353
• Length: 344
• Species: Saccharomyces cerevisiae
• Alignment Length: 304
• Identity: 73/304 - (24%)
• Similarity: 122/304 - (40%)
• Gaps: 81/304 - (26%)

  Fly    13 VISTGNIIATELGQRKSNEELY----DGLKIT---LHTDSTAERVVVEKE------------ID- 57
            |.||.||:...|..:.:  |:|    :|::|.   |.|.:..|::...|:            ||
Yeast     5 VASTENIVENMLHPKTT--EIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDT 67

  Fly    58 ----ELHGRVQRATQELTTRLTENG---RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVD 115
                |....|..|.:|    |.|:|   |.::.|..|::  ....:.|::::.|.|..|.:.:||
Yeast    68 AWAYETEPFVGEAIKE----LLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVD 126

  Fly   116 NVVLAYH----------PNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTL 170
              :|..|          |..::     ...|.|..:......|.:          .:..|.||.|
Yeast   127 --LLLQHWPLCFEKIKDPKGIS-----GLVKTPVDDSGKTMYAAD----------GDYLETYKQL 174

  Fly   171 EQYAL---KQQITQLGIADLDAAALEELHNSAQVVPTIAQVNLSTCCVVPP-ELQEFCTAHDI-- 229
            |:..|   ..::..:|:::.....||.|....:|.||:.||  .|...:|. ||::||..|||
Yeast   175 EKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQV--ETHPHLPQMELRKFCFMHDILL 237

  Fly   230 ----QLNTHSDPELLLPVEQFDGLVPGYTI---DWTLRYQVHVR 266
                .|.:|..|.|.:|:.:  .|...|.:   |..:.|  |:|
Yeast   238 TAYSPLGSHGAPNLKIPLVK--KLAEKYNVTGNDLLISY--HIR 277

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	40/175 (23%)
ARA1	NP_009707.3	AKR_AKR3C1	22..321	CDD:381345	67/285 (24%)