Protein Alignment Gclm and AKR1E2

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: XP_011518017.1
• Gene: AKR1E2 / 83592
• HGNCID: 23437
• Length: 341
• Species: Homo sapiens
• Alignment Length: 245
• Identity: 41/245 - (16%)
• Similarity: 83/245 - (33%)
• Gaps: 82/245 - (33%)

  Fly    79 RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVATTKPP----- 138
            |.::.|..|::...|....|..|..:.|..|.:.::| :.|.:.|...         |||
Human    82 REDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLD-LYLIHWPMGF---------KPPHPEWI 136

  Fly   139 --CSE----------------DSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIA 185
              |||                :||:...::          .:..:.::.:|...:...:..:|::
Human   137 MSCSELSFCLSHPRVQDLPLDESNMVIPSD----------TDFLDTWEAMEDLVITGLVKNIGVS 191

  Fly   186 DLDAAALEE-----------LHNSAQVVPTIAQVNLSTCCVVPPELQEFCTAHDIQLNTHS---- 235
            :.:...||.           |.|..:..|.:.|.||.:          ||.:.|:.:..:.
Human   192 NFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLIS----------FCQSRDVSVTAYRPLGG 246

  Fly   236 --------DPELLLPVEQFDGLVPGYTIDWTLRYQVHVRCRGVLTAKGYI 277
                    |..::..:.:..|..|...:   :|:|:.   |.|:...|.|
Human   247 SCEGVDLIDNPVIKRIAKEHGKSPAQIL---IRFQIQ---RNVIVIPGSI 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	33/204 (16%)
AKR1E2	XP_011518017.1	ARA1	34..322	CDD:223729	41/245 (17%)
		Tas	42..314	CDD:223739	41/245 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900