Protein Alignment Gclm and Akr1a1

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_067448.1
• Gene: Akr1a1 / 58810
• MGIID: 1929955
• Length: 325
• Species: Mus musculus
• Alignment Length: 210
• Identity: 46/210 - (21%)
• Similarity: 83/210 - (39%)
• Gaps: 52/210 - (24%)

  Fly    79 RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVATTKPPCSEDS 143
            |.|:.:.:|::..:|..|.|..|:.:.|..|.:.::| :.|.:.|.|
Mouse    72 REELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLD-LYLMHWPYA------------------ 117

  Fly   144 NVSRATNWSQRNGKEGV----AELKELYKTLEQYALKQQITQLGIADLDAAALEELHNSAQVVPT 204
             ..|..|...:|....|    ...||.:|.||....|..:..||:::.::..::::.:.|.|.|.
Mouse   118 -FERGDNPFPKNADGTVRYDSTHYKETWKALEVLVAKGLVKALGLSNFNSRQIDDVLSVASVRPA 181

  Fly   205 IAQVNLSTCC---VVPPELQEFCTAHDIQLNTHS-------------DPELL-----LPVEQFDG 248
            :.||.    |   :...||...|.|..:::..:|             :|.||     |.:.:..|
Mouse   182 VLQVE----CHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPVVLALAEKHG 242

  Fly   249 LVPGYTIDWTLRYQV 263
            ..|...:   ||:||
Mouse   243 RSPAQIL---LRWQV 254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	36/178 (20%)
Akr1a1	NP_067448.1	ARA1	1..303	CDD:223729	46/210 (22%)
		Tas	9..291	CDD:223739	46/210 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900