Protein Alignment Gclm and Akr1c12

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001014262.3
• Gene: Akr1c12 / 364773
• RGDID: 1359406
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 244
• Identity: 48/244 - (19%)
• Similarity: 98/244 - (40%)
• Gaps: 48/244 - (19%)

  Fly     5 ITKKYQNVVISTGNIIAT---------ELGQRKSNEELYDGLKITLHTDSTAERVVVEKEIDE-L 59
            ::.|...|.::.|:.|..         |:.:.||.|..:..:.:......||....||:||.: :
  Rat     1 MSSKLHCVKLNDGHFIPALGFGTYKPKEVPKSKSLEAAHLAIDVGYRHIDTASAYQVEEEIGQAI 65

  Fly    60 HGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPN 124
            ..:::....:         |.::.|..|::.:...||.|..|:|:.|..|.:.:|| :.|.::|
  Rat    66 QSKIKAGVVK---------RKDMFITTKLWCSCFRTEMVRPALEKSLKNLQLDYVD-LFLIHYP- 119

  Fly   125 AVATATPVATT--KPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADL 187
                 .|:.::  :.|..|.......|           .:..:.::.||:......:..:|:::.
  Rat   120 -----VPIKSSVDESPLDEKGKFLLDT-----------VDFCDTWEMLEKCKDAGLVKSIGVSNF 168

  Fly   188 DAAALEELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQL 231
            :...||.|.|  ..:..|...||.    |   :...:|.::|.:.||.|
  Rat   169 NHKQLERLLNKPGLKYKPVCNQVE----CHLYLNQSKLLDYCKSKDIVL 213

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	34/160 (21%)
Akr1c12	NP_001014262.3	ARA1	8..305	CDD:223729	47/237 (20%)
		Tas	16..297	CDD:223739	45/229 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900