DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gclm and gclm

DIOPT Version :9

Sequence 1:	NP_001262845.1	Gene:	Gclm / 248194	FlyBaseID:	FBgn0046114	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	XP_009302077.1	Gene:	gclm / 333974	ZFINID:	ZDB-GENE-030131-5906	Length:	274	Species:	Danio rerio

Alignment Length:	285	Identity:	88/285 - (30%)
Similarity:	140/285 - (49%)	Gaps:	45/285 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISTGNIIATELGQRK----SNEELYDGLKITLHTDSTAERVVVEKEIDELHGRVQRATQELTTRL 74
            :.|||::.....::|    .:|||.|.::.||....||....::.|:..:   :..:..|.|..:
Zfish    19 LHTGNLVNRSRLKKKCPSSPSEELQDCIQGTLSEWFTAMPSSLDSELPSV---LDCSIPENTEAI 80

  Fly    75 TENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVATTKPPC 139
            |...|.|:.:..|:||......|:..||:.....|.|:.:|:|::|                ||.
Zfish    81 TPEEREELKVSVKLFLTEWDCSSIRSAVDMACLSLGVSQLDSVIIA----------------PPS 129

  Fly   140 SEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADLDAAALEELHNSA-QVVP 203
            ..:......|:            |:.|::.||.....|:|..:|.:|||...||:|:|.| |:.|
Zfish   130 LPEGESQTLTH------------LQPLWQELESLVQSQKIAAIGTSDLDKTLLEQLYNWAQQIKP 182

  Fly   204 TIAQVNLSTCCVVPPELQEFCTAHDIQLNTHSDPELLLPVEQFDGLVPG---------YTIDWTL 259
            :..||||::|||:||:|..|....||||.|||||:.|:....|...|.|         :.::|.|
Zfish   183 SSNQVNLASCCVMPPDLTAFAKEFDIQLLTHSDPKELISAAGFQEAVQGSSQELQVDDWRLEWVL 247

  Fly   260 RYQVHVRCRGVLTAKGYIVGASRSS 284
            ||.:.|:.||::.||||||.|.:|:
Zfish   248 RYSIIVKSRGIIKAKGYIVHAKKSN 272

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	52/159 (33%)
gclm	XP_009302077.1	Aldo_ket_red	<85..255	CDD:294321	62/197 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170594897
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1557
Inparanoid	1	1.050	133	1.000	Inparanoid score	I4583
OMA	1	1.010	-	-		QHG48881
OrthoDB	1	1.010	-	-		D1516283at2759
OrthoFinder	1	1.000	-	-		FOG0006260
OrthoInspector	1	1.000	-	-		oto40041
orthoMCL	1	0.900	-	-		OOG6_106072
Panther	1	1.100	-	-	LDO	PTHR13295
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4224
SonicParanoid	1	1.000	-	-		X5208
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800