Protein Alignment Gclm and Akr1c1

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001028869.1
• Gene: Akr1c1 / 307092
• RGDID: 1306847
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 307
• Identity: 69/307 - (22%)
• Similarity: 120/307 - (39%)
• Gaps: 70/307 - (22%)

  Fly     5 ITKKYQNVVISTGNII-----ATELGQRKSNEELYDGLKITL-----HTDSTAERVVVEKEID-E 58
            :..|.|.|.:|.|:.|     .|...:.....:..:..||.:     |.||.|. ...|||:. .
  Rat     1 MNSKQQTVRLSDGHFIPVLGFGTYAPREVPKSKALEATKIAIDAGFRHIDSAAV-YQNEKEVGLA 64

  Fly    59 LHGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHP 123
            :..::...|.:         |.:|...:|::...:..|.|...:|:.|..|.:.:|| :.|.:.|
  Rat    65 IRSKIADGTVK---------REDIFYTSKVWCTFNHPERVQVCLEQSLKQLQLEYVD-LYLIHFP 119

  Fly   124 NAVATATPVATTKPPCSEDSNVSRATNWSQRNGK--EGVAELKELYKTLEQYALKQQITQLGIAD 186
            .|:         ||  .||...      ...|.|  ..|.::.:.:|.:|:.........:|:::
  Rat   120 MAL---------KP--EEDLKA------KDENEKLLFDVVDICDTWKAMEKCKDAGLAKSIGVSN 167

  Fly   187 LDAAALEELHNSAQVV--PTIAQVNLSTCC---VVPPELQEFCTAHDI------QLNTHSDPELL 240
            .:...||::.|...:.  |...||.    |   :...:|.:||.:.||      .|.:|.:...:
  Rat   168 FNRRQLEKILNKPGLKHRPVCNQVE----CHPYLNQRKLLDFCKSKDIVLVAYSALGSHRETRCV 228

  Fly   241 ---LPVEQFDGLVPGYT--IDWT-----LRYQVHVRCRGVLT-AKGY 276
               |||...|.::....  .:||     ||||:.   |||:. ||.:
  Rat   229 DKSLPVLLADPVLCAIAKKYNWTPALIALRYQLE---RGVVVLAKSF 272

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	37/171 (22%)
Akr1c1	NP_001028869.1	ARA1	5..305	CDD:223729	68/303 (22%)
		Tas	16..297	CDD:223739	64/292 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900