Protein Alignment Gclm and Akr1b10

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001013102.1
• Gene: Akr1b10 / 296972
• RGDID: 1308277
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 206
• Identity: 42/206 - (20%)
• Similarity: 81/206 - (39%)
• Gaps: 46/206 - (22%)

  Fly    53 EKEIDELHGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNV 117
            |.|:.|   .:|...:|...|     |.::.|.:|::........|.:|.::.|..|.:.::| :
  Rat    52 ESEVGE---AIQEKIKEKAVR-----REDLFIVSKLWPTFFEKSLVKKAFQKTLLDLKLDYLD-L 107

  Fly   118 VLAYHPNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQL 182
            .|.:.|....:.....    |..:..|| ..:.::..:..||:.||      ::|..:|    .|
  Rat   108 YLIHWPQGFQSGNVFL----PTDDKGNV-LTSKYTFLDAWEGMEEL------VDQGLVK----AL 157

  Fly   183 GIADLDAAALEELHNSAQV--VPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTHS------- 235
            |:::.:...:|.|.|...:  .|...||.    |   :...:|.::|.:..|.:..:|
  Rat   158 GVSNFNHFQIERLLNKPGLKHKPVTNQVE----CHPYLTQEKLIQYCHSKGIVVTAYSPLGSPDR 218

  Fly   236 ------DPELL 240
                  ||.||
  Rat   219 PSAKPEDPVLL 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	31/160 (19%)
Akr1b10	NP_001013102.1	AKR_AKR1B1-19	10..316	CDD:381333	42/206 (20%)