Protein Alignment Gclm and Akr1b8

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_775159.1
• Gene: Akr1b8 / 286921
• RGDID: 708475
• Length: 316
• Species: Rattus norvegicus
• Alignment Length: 211
• Identity: 45/211 - (21%)
• Similarity: 82/211 - (38%)
• Gaps: 56/211 - (26%)

  Fly    53 EKEIDELHGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNV 117
            |.|:.|   .:|...:|...|     |.::.|.:|::......:.:.:|.::.|..|.:.::| :
  Rat    52 ENEVGE---AIQEKIKEKAVR-----REDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLD-L 107

  Fly   118 VLAYHPNAVATATPVATTKPPCSEDSNV--SRAT---NWSQRNGKEGVAELKELYKTLEQYALKQ 177
            .|.:.|........:.    |..|..||  |:.|   .|      ||:.||      ::|..:|
  Rat   108 YLIHWPQGFQAGKELF----PKDEQGNVLPSKTTFLEAW------EGMEEL------VDQGLVK- 155

  Fly   178 QITQLGIADLDAAALEELHNSAQV--VPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTHS-- 235
               .||:::.:...:|.|.|...:  .|...||.    |   :...:|.::|.:..|.:..:|
  Rat   156 ---ALGVSNFNHFQIERLLNKPGLKHKPVTNQVE----CHPYLTQEKLIQYCHSKGIVVTAYSPL 213

  Fly   236 -----------DPELL 240
                       ||.||
  Rat   214 GSPDRPRAKPDDPSLL 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	36/181 (20%)
Akr1b8	NP_775159.1	ARA1	1..297	CDD:223729	45/211 (21%)
		Tas	16..289	CDD:223739	45/211 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900