Protein Alignment Gclm and Akr1c13

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_001413556.1
• Gene: Akr1c13 / 27384
• MGIID: 1351662
• Length: 324
• Species: Mus musculus
• Alignment Length: 238
• Identity: 46/238 - (19%)
• Similarity: 93/238 - (39%)
• Gaps: 44/238 - (18%)

  Fly     7 KKYQNVVIS-----TGNIIATELGQRKSNEELYDGLKITLHTDSTAERVVVEKEIDE-LHGRVQR 65
            |.:.|.:::     ..:::...:.:.||.|.....|.:......||....||:||.: :..:::.
Mouse     8 KTFWNFIVNHYDGEKEDLVKINVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSKIKA 72

  Fly    66 ATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATAT 130
            ...:         |.::.|..|::......|.|..|:|:.|..|.:.:||..::.|
Mouse    73 GVVK---------REDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHY--------- 119

  Fly   131 PVATTKPPCSEDSNVSRATNWSQRNGKE--GVAELKELYKTLEQYALKQQITQLGIADLDAAALE 193
            ||    |..|.|::..     ....||.  ...:..:.::.||:......:..:|:::.:...||
Mouse   120 PV----PMKSGDNDFP-----VNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLE 175

  Fly   194 ELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQL 231
            .:.|  ..:..|...||.    |   :...:|.::|.:.||.|
Mouse   176 RILNKPGLKYKPVCNQVE----CHLYLNQRKLLDYCESKDIVL 214

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	34/160 (21%)
Akr1c13	NP_001413556.1	None