DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gclm and E01A2.1

DIOPT Version :9

Sequence 1:	NP_001262845.1	Gene:	Gclm / 248194	FlyBaseID:	FBgn0046114	Length:	285	Species:	Drosophila melanogaster
Sequence 2:	NP_001367719.1	Gene:	E01A2.1 / 171998	WormBaseID:	WBGene00017084	Length:	290	Species:	Caenorhabditis elegans

Alignment Length:	287	Identity:	77/287 - (26%)
Similarity:	121/287 - (42%)	Gaps:	58/287 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 ISTGNIIA-TELGQRK---SNEELYDGLKITLHTDSTAERVVVEKE------IDELHGRVQRATQ 68
            :.|||:.. |:|..|:   |.|||...|.:.|.::..|:..   ||      .|..|
Worm    33 LHTGNVNGYTQLKVRRFETSAEELAACLDLQLSSNPIADDF---KENSCLLLCDNDH-------- 86

  Fly    69 ELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATATPVA 133
                 :....|:||.|..|:||:....:.::|||..|...|....::.::|::        ..:.
Worm    87 -----IDNYERDEIKITMKVFLSAWDVQQIDQAVTSLKEQLKTKDIEVLILSF--------PELD 138

  Fly   134 TTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQLGIADLDAAALEELHNS 198
            .......||.|    ..|.::        :|.||..:|:.....:|..:|::|..|..|:.:.:.
Worm   139 LIDGESEEDEN----NRWFEK--------VKPLYTYMEKLVETSEIASIGVSDFSARQLKTIIDH 191

  Fly   199 AQVVPTIAQVNLSTCCVVPPELQEFCTAHDIQLNTHSDP------ELLLPVEQFDG------LVP 251
            ..|.|:|..|.|..||.||||||.....:|:||..|:||      .:.....:.|.      ..|
Worm   192 FDVKPSINHVRLDGCCQVPPELQALANDNDVQLLVHNDPTPFPTNNIFKTFCEIDSGSQKAVCSP 256

  Fly   252 GYTIDWTLRYQVHVRCRGVLTAKGYIV 278
            .:...|..||.|.||.|.::|:|||||
Worm   257 LFETTWLSRYSVWVRKRSIMTSKGYIV 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	45/164 (27%)
E01A2.1	NP_001367719.1	AKR_SF	<92..>224	CDD:412396	40/151 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160166453
Domainoid	1	1.000	65	1.000	Domainoid score	I6646
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H1557
Inparanoid	1	1.050	87	1.000	Inparanoid score	I3716
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48881
OrthoDB	1	1.010	-	-		D1516283at2759
OrthoFinder	1	1.000	-	-		FOG0006260
OrthoInspector	1	1.000	-	-		oto18791
orthoMCL	1	0.900	-	-		OOG6_106072
Panther	1	1.100	-	-	LDO	PTHR13295
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4224
SonicParanoid	1	1.000	-	-		X5208
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.940