Protein Alignment Gclm and Akr1c3

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_612519.1
• Gene: Akr1c3 / 171516
• RGDID: 708428
• Length: 323
• Species: Rattus norvegicus
• Alignment Length: 317
• Identity: 63/317 - (19%)
• Similarity: 117/317 - (36%)
• Gaps: 99/317 - (31%)

  Fly     5 ITKKYQNVVISTGNII--------ATELGQRKSNEELYDGLKITL-----HTDSTAERVVVEKEI 56
            :..|.|.:.::.|:.|        |||...||.:.|   ..||.:     |.|.:
  Rat     1 MNSKIQKMELNDGHSIPVLGFGTYATEENLRKKSME---STKIAIDVGFRHIDCS---------- 52

  Fly    57 DELHGRVQRATQELTTRLTENG---RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVV 118
             .|:...:...|.:.::: |:|   |.:|...:|::...|..|.|..::|..|..|::.:|| :.
  Rat    53 -HLYQNEEEIGQAIVSKI-EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVD-LY 114

  Fly   119 LAYHPNAVATATPVATTKP-----PCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQ 178
            |.:.|         .:.||     |..|..|:...|           .:|.:.::.:|:......
  Rat   115 LIHFP---------VSLKPGDELLPQDEHGNLILDT-----------VDLCDTWEAMEKCKDAGL 159

  Fly   179 ITQLGIADLDAAALEELHNSAQVV--PTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTH---- 234
            ...:|:::.:...||::.|...:.  |...||.    |   :...:|..:|..:||.|..:
  Rat   160 AKSIGVSNFNRRQLEKILNKPGLKHRPVCNQVE----CHLYLNQSKLLAYCKMNDIVLVAYGALG 220

  Fly   235 ----------------SDPELLLPVEQF---DGLVPGYTIDWTLRYQVHVRCRGVLT 272
                            .||.|....:::   ..|:       .||||:.   ||::|
  Rat   221 TQRYKYCINEDTPVLLDDPILCTMAKKYKRTPALI-------ALRYQLE---RGIVT 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	35/188 (19%)
Akr1c3	NP_612519.1	AKR_AKR1C1-35	6..308	CDD:381334	62/312 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900