Protein Alignment Gclm and Akr1b8

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_032038.1
• Gene: Akr1b8 / 14187
• MGIID: 107673
• Length: 316
• Species: Mus musculus
• Alignment Length: 206
• Identity: 40/206 - (19%)
• Similarity: 82/206 - (39%)
• Gaps: 46/206 - (22%)

  Fly    53 EKEIDELHGRVQRATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNV 117
            |.|:.|   .:|...:|...:     |.::.|.:|::......:.:.:|.::.|..|.:.::| :
Mouse    52 ENEVGE---AIQEKIKEKAVQ-----REDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLD-L 107

  Fly   118 VLAYHPNAVATATPVATTKPPCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQITQL 182
            .|.:.|..:   .|.....|...:...::..|.:.:  ..||:.||      ::|..:|    .|
Mouse   108 YLIHWPQGL---QPGKELFPKDDQGRILTSKTTFLE--AWEGMEEL------VDQGLVK----AL 157

  Fly   183 GIADLDAAALEELHNSAQV--VPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTHS------- 235
            |:::.:...:|.|.|...:  .|...||.    |   :...:|.::|.:..|.:..:|
Mouse   158 GVSNFNHFQIERLLNKPGLKHKPVTNQVE----CHPYLTQEKLIQYCHSKGISVTAYSPLGSPDR 218

  Fly   236 ------DPELL 240
                  ||.||
Mouse   219 PSAKPEDPSLL 229

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	30/160 (19%)
Akr1b8	NP_032038.1	AKR_AKR1B1-19	10..316	CDD:381333	40/206 (19%)