Protein Alignment Gclm and Akr1b7

DIOPT Version :10

• Sequence 1: NP_732780.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_033861.2
• Gene: Akr1b7 / 11997
• MGIID: 101918
• Length: 316
• Species: Mus musculus
• Alignment Length: 189
• Identity: 36/189 - (19%)
• Similarity: 74/189 - (39%)
• Gaps: 35/189 - (18%)

  Fly    53 EKEIDELHGRVQRATQELTTRLTENG--RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVD 115
            |.|:.|       |.||   ::.||.  |.::.|.:|::........|.:|.:..|..|.:.::|
Mouse    52 ENEVGE-------AIQE---KIKENAVKREDLFIVSKLWATFFEKSLVKKAFQNTLSDLKLDYLD 106

  Fly   116 NVVLAYHPNAVATATPVATTKPPCSEDSNV--SRATNWSQRNGKEGVAELKELYKTLEQYALKQQ 178
             :.|.:.|........:.    |......|  |::|             ..:.::.:|:...:..
Mouse   107 -LYLVHWPQGFQAGNALL----PKDNKGKVLLSKST-------------FLDAWEAMEELVDQGL 153

  Fly   179 ITQLGIADLDAAALEELHNSAQV--VPTIAQVNLSTCCVVPPELQEFCTAHDIQLNTHS 235
            :..|||::.:...:|.|.|...:  .|...|:. |...:...:|.::|.:..|.:..:|
Mouse   154 VKALGISNFNHFQIERLLNKPGLKHKPVTNQIE-SHPYLTQEKLIQYCQSKGIAVTAYS 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_732780.1	AKR_SF	<79..>235	CDD:444925	27/159 (17%)
Akr1b7	NP_033861.2	AKR_AKR1B1-19	10..316	CDD:381333	36/189 (19%)