Protein Alignment Gclm and Akr1c14

DIOPT Version :9

• Sequence 1: NP_001262845.1
• Gene: Gclm / 248194
• FlyBaseID: FBgn0046114
• Length: 285
• Species: Drosophila melanogaster
• Sequence 2: NP_598833.1
• Gene: Akr1c14 / 105387
• MGIID: 2145458
• Length: 323
• Species: Mus musculus
• Alignment Length: 302
• Identity: 58/302 - (19%)
• Similarity: 114/302 - (37%)
• Gaps: 85/302 - (28%)

  Fly    12 VVISTGNII-----ATELGQRKSNEELYDGLKITL-----HTDSTAERVVVEKEIDE-LHGRVQR 65
            ||::.|:.|     .|.:..:...:||....||.:     |.|| |....:|:|:.: :..:::.
Mouse     8 VVLNDGHFIPALGFGTTVPDKVPKDELIKATKIAIDTGFRHFDS-AYLYQIEEEVGQAIRSKIED 71

  Fly    66 ATQELTTRLTENGRNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVVLAYHPNAVATAT 130
            .|.:         |.:|...:|::...|..|.|...:|:.|....:.:|| :.:.:.|.|:...
Mouse    72 GTVK---------REDIFYTSKLWSTFHRPELVRSCLEKTLKNAQLDYVD-LYIIHFPMALQPG- 125

  Fly   131 PVATTKPPCSEDSNVSRATNWSQRNGK---EGVAELKELYKTLEQYALKQQITQLGIADLDAAAL 192
                       |....|     ..:||   |.| :|.:.::.:|:.........:|:::.:...|
Mouse   126 -----------DKLFPR-----DEHGKLLAEAV-DLCDTWEAMEKCKDAGLAKSIGVSNFNFRQL 173

  Fly   193 EELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTH------------------ 234
            |.:.|  ..:..|...||.    |   :...::.::|.:.||.|.::
Mouse   174 ETILNKPGLKYKPVCNQVE----CHLYLNQSQMLDYCKSKDIILVSYCTLGSSRDKIWVDQKSPV 234

  Fly   235 --SDPELLL---PVEQFDGLVPGYTIDWTLRYQVHVRCRGVL 271
              .||.|..   ..:|...|:       .:|||:.   ||::
Mouse   235 LLDDPVLCAMANKYKQTPALI-------AIRYQLQ---RGIV 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gclm	NP_001262845.1	Aldo_ket_red	<79..>238	CDD:294321	33/186 (18%)
Akr1c14	NP_598833.1	AKR_AKR1C1-35	6..308	CDD:381334	58/302 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0656
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900