DRSC/TRiP Functional Genomics Resources

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Protein Alignment Gclm and Akr1c18

DIOPT Version :9

Sequence 1:NP_001262845.1 Gene:Gclm / 248194 FlyBaseID:FBgn0046114 Length:285 Species:Drosophila melanogaster
Sequence 2:NP_598827.1 Gene:Akr1c18 / 105349 MGIID:2145420 Length:323 Species:Mus musculus


Alignment Length:322 Identity:63/322 - (19%)
Similarity:118/322 - (36%) Gaps:100/322 - (31%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 ITKKYQNVVISTGNII--------ATELGQRKSNEELYDGLKITL-----HTDSTAERVVVEKEI 56
            :..|.|.:.::.|:.|        |||...:|.:.|   ..||.:     |.|.:          
Mouse     1 MNSKIQKIELNDGHSIPVLGFGTYATEEHLKKKSME---STKIAIDVGFCHIDCS---------- 52

  Fly    57 DELHGRVQRATQELTTRLTENG---RNEISIGAKIFLNRHSTESVNQAVEELLHILSVTHVDNVV 118
             .|:...:...|.:.::: |:|   |.:|...:|::...|..|.|..::|..|..|::.:|| :.
Mouse    53 -HLYQNEEEIGQAILSKI-EDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVD-LY 114

  Fly   119 LAYHPNAVATATPVATTKP-----PCSEDSNVSRATNWSQRNGKEGVAELKELYKTLEQYALKQQ 178
            |.:.|         .:.||     |..|..|:...|           .:|.:.::.:|:......
Mouse   115 LIHFP---------VSLKPGNELLPKDEHGNLIFDT-----------VDLCDTWEAMEKCKDAGL 159

  Fly   179 ITQLGIADLDAAALEELHN--SAQVVPTIAQVNLSTCC---VVPPELQEFCTAHDIQLNTH---- 234
            ...:|:::.:...||.:.|  ..:..|...||.    |   :...:|..:|..:||.|..:    
Mouse   160 AKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVE----CHLYLNQSKLLAYCKMNDIVLVAYGALG 220

  Fly   235 ----------------SDPELLLPVEQF---DGLVPGYTIDWTLRYQVHVRCRGVLT-AKGY 276
                            .||.|....:::   ..|:       .||||:.   ||::. ||.:
Mouse   221 TQRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALI-------ALRYQLD---RGIVALAKSF 272

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
GclmNP_001262845.1 Aldo_ket_red <79..>238 CDD:294321 35/188 (19%)
Akr1c18NP_598827.1 ARA1 7..310 CDD:223729 61/316 (19%)
Tas 15..297 CDD:223739 60/308 (19%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG0656
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

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