DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gos28 and Gosr1

DIOPT Version :9

Sequence 1:	NP_650739.2	Gene:	Gos28 / 248102	FlyBaseID:	FBgn0044871	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_446036.1	Gene:	Gosr1 / 94189	RGDID:	71093	Length:	250	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	115/248 - (46%)
Similarity:	162/248 - (65%)	Gaps:	18/248 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GGSSY-DVLRKQARSLENEIDLKLVAFSKI----GAGSGGGGSGGLGGVDTSPLLG----EHVFD 57
            |.|:| :.||||||.||||:|||||:|||:    ...|...|.......||:|||.    :.:|:
  Rat     4 GTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSSARDGGRDRYSSDTTPLLNGSSQDRMFE 68

  Fly    58 SLSEEIEQMLEKLSSLNESMSD------LPASGAAAMHTLQRHREILQGYRQEFNKICANHTMRI 116
            :::.||||:|.:|:.:|:.|::      :|:..||.||||||||:|||.|..||:|..||. |.|
  Rat    69 TMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANF-MAI 132

  Fly   117 EREELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQA 179
            ...|.|.||.........|.||:|.|  |::|||..||.::..|:.:.|:||:.|::::.:||..
  Rat   133 RERENLMGSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRGM 197

  Fly   180 FKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN 232
            .|.:.::.|.::||||.::|||||||::|||||||||.|||.|.||||||||:
  Rat   198 LKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gos28	NP_650739.2	SNARE	142..207	CDD:419871	27/66 (41%)
Gosr1	NP_446036.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..59		6/21 (29%)
Gosr1	NP_446036.1	SNARE_GS28	160..225	CDD:277217	26/64 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336870
Domainoid	1	1.000	101	1.000	Domainoid score	I6822
eggNOG	1	0.900	-	-		E1_KOG3208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37977
Inparanoid	1	1.050	195	1.000	Inparanoid score	I3741
OMA	1	1.010	-	-		QHG55290
OrthoDB	1	1.010	-	-		D1319902at2759
OrthoFinder	1	1.000	-	-		FOG0004151
OrthoInspector	1	1.000	-	-		oto96904
orthoMCL	1	0.900	-	-		OOG6_102989
Panther	1	1.100	-	-	LDO	PTHR21094
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5179
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810