DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Gos28 and Gosr1

DIOPT Version :9

Sequence 1:	NP_650739.2	Gene:	Gos28 / 248102	FlyBaseID:	FBgn0044871	Length:	232	Species:	Drosophila melanogaster
Sequence 2:	NP_058090.2	Gene:	Gosr1 / 53334	MGIID:	1858260	Length:	250	Species:	Mus musculus

Alignment Length:	249	Identity:	118/249 - (47%)
Similarity:	167/249 - (67%)	Gaps:	20/249 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GGSSY-DVLRKQARSLENEIDLKLVAFSKI-----GAGSGGGGSGGLGGVDTSPLLG----EHVF 56
            |.|:| :.||||||.||||:|||||:|||:     .:||..||...... ||:|||.    :.:|
Mouse     4 GTSNYWEDLRKQARQLENELDLKLVSFSKLCTSYSHSGSRDGGRDRYSS-DTTPLLNGSSQDRMF 67

  Fly    57 DSLSEEIEQMLEKLSSLNESMSD------LPASGAAAMHTLQRHREILQGYRQEFNKICANHTMR 115
            ::::.||||:|.:|:.:|:.|::      :|:..||.||||||||:|||.|..||:|..||.|..
Mouse    68 ETMAIEIEQLLARLTGVNDKMAEYTHSAGVPSLNAALMHTLQRHRDILQDYTHEFHKTKANFTAI 132

  Fly   116 IEREELLRGSGLATSSGSPSISGLNRR--EMYLKESGHLNSASHLVNDQINIAIETRDHLHAQRQ 178
            .|||.|: ||.........|.||:|.|  |::|||..||.::..|:.:.|:||:.|::::.:||.
Mouse   133 RERENLM-GSVRKDIESYKSGSGVNNRRTELFLKEHDHLRNSDRLIEETISIAMATKENMTSQRG 196

  Fly   179 AFKRLQTRFNDISNRFPLISSLIQRINIKKRRDSLILGAVIGFCVILLLLYAFN 232
            ..|.:.::.|.::||||.::|||||||::|||||||||.|||.|.||||||||:
Mouse   197 MLKSIHSKMNTLANRFPAVNSLIQRINLRKRRDSLILGGVIGICTILLLLYAFH 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Gos28	NP_650739.2	SNARE	142..207	CDD:419871	27/66 (41%)
Gosr1	NP_058090.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	37..59		8/22 (36%)
Gosr1	NP_058090.2	SNARE_GS28	160..225	CDD:277217	26/64 (41%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833315
Domainoid	1	1.000	106	1.000	Domainoid score	I6603
eggNOG	1	0.900	-	-		E1_KOG3208
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37977
Inparanoid	1	1.050	200	1.000	Inparanoid score	I3776
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55290
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004151
OrthoInspector	1	1.000	-	-		oto93362
orthoMCL	1	0.900	-	-		OOG6_102989
Panther	1	1.100	-	-	LDO	PTHR21094
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R505
SonicParanoid	1	1.000	-	-		X5179
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790